Lockjaw from a metastatic uterine leiomyosarcoma- case report and review of the literature

BMC Women's Health

Table 2 All cases of uterine LMS metastasising to the mandible found in literature

Year	Author	Age	Metastatic Sites	Treatment of Uterine Primary	Treatment of Metastases	Disease free interval	Survival from diagnosis	Survival after appearance of metastasis	Cause of death	First symptoms of metastasis	Method of diagnosis
1988	Tsounias et al.	67	Mandible, lung, bones	S	S (curettage)	12 months (uterine then mandible)	1 year 2 months	2 months	Metastatic disease	Pain in left mandible	X-ray then surgery
2000	Dry SM et al.	45	Maxilla, mandible	None	S + R	1 month (uterine after mandible)	11 months	11 months	Metastatic disease	Loose teeth + left nasal congestion	Unknown
2013	Fernandez-Barriales et al.	49	Mandible, masseter, maxilla, lung, liver, vertebral body, lymph node	C + R	C + R	0 months (simultaneous uterine + mandible)	1 year 6 months	18 months	Metastatic disease	Hypoesthesia in inferior alveolar nerve territory (NCS)	Observation of mass then OPG
2015	Hope et al.	54	Mandible, left masseter, humerus, duodenum	S	S + R + C	14 months (uterine then mandible)	4 years 2 months	3 years	Progressive metastatic disease	Left lower lip hypoesthesia (NCS)	Tooth extraction, biopsy of tissue

Year of article publication, author, age of patient at diagnosis, metastatic sites of the uterine LMS, treatment of primary tumour and subsequent metastases, survival time from diagnosis, survival time after metastatic diagnosis, cause of death, first reported symptom of metastatic spread, method of metastatic diagnosis.

ISSN: 1472-6874