Table 5 Comparison of workflow efficiencies and throughput on the cobas 4800 and cobas 6800 systems (including p 480 instruments)
p 480 v1 + 4800 | p 480 v2 + 6800 | |
|---|---|---|
Preanalytical step: | ||
- samples’ aliquoting | performed by × 480 | performed by p 480 |
Analytical steps: | ||
- instrument loading (reagents) | single-use vials with pouring (10 min) | re-usable reagent cartridges, no preparation needed |
- reagent on-board stability | discarded after run | 90 days |
- user interaction | vials loading/unloading at each run | cartridge loading - unloading when empty/expired |
- instrument loading (samples) | 94 uncapped primary vials | up to 280 secondary tubes |
- throughput (per 8 h) | 192 | 384 |
- time to first 96 results | 4.9 h | < 3.5 h |
- time to each additional 96 results | 160 min | 90 min |
- hands-on-time (8 h) | 60 min | 30 min |
Instrumentation maintenance | daily | monthly |
Amount of waste produced | ~ 2.6 l of liquids | ~ 1.7 l of liquids / ~ 40% less of sol |