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Table 4 Multiple linear regression analysis with sleep disturbance as dependent variable

From: Associations between menopausal hormone therapy and sleep disturbance in women during the menopausal transition and post-menopause: data from the Norwegian prescription database and the HUNT study

 

Univariate

Multivariate

Independent variables

B

95% CI

p-value

B

95% CI

p-value

MHT (ref. = non-user)

0.14

0.03–0.24

< 0.001

0.04

−0.06 – 0.14

0.41

Sleep medication (ref. = non-user)

1.31

1.24–1.38

< 0.001

0.84

0.77–0.91

< 0.001

Age (years) (ref. = 45–54)

 55–64

0.38

0.31–0.44

< 0.001

0.22

0.27–0.76

< 0.001

 65–75

0.39

0.32–0.44

< 0.001

0.20

0.13–0.28

< 0.001

Living with partner/others (ref. = living alone)

− 0.19

− 0.26 – − 0.12

< 0.001

− 0.03

− 0.10 – 0.04

0.43

Exercise (ref. = <once a week)

 Once a week

−0.17

− 0.26 – - 0.07

0.001

0.01

−0.08 – 0.10

0.85

 2–3 times a week

−0.20

−0.28 – - 0.11

< 0.001

0.03

−0.06 – 0.10

0.62

 Daily

−0.12

−0.21 – - 0.02

0.01

0.17

0.02–0.20

0.02

Non-smoker (ref. = current smoker)

0.01

−0.06 – 0.07

0.85

−0.18

−0.24 – − 0.12

< 0.001

Alcohol (ref. = no use)

− 0.11

− 0.18 – − 0.05

0.001

0.12

0.06–0.19

< 0.001

Hospital Anxiety and Depression Scale (HADS)

 Anxiety

0.15

0.14–0.16

< 0.001

0.12

0.11–0.13

< 0.001

 Depression

0.06

0.04–0.07

< 0.001

0.02

0.01–0.03

0.002

Satisfaction with life (higher levels indicate less life satisfaction)

0.43

0.41–0.46

< 0.001

0.07

0.04–0.10

< 0.001

Self-assessed health (higher levels indicate better health)

−0.73

− 0.77 – − 0.68

< 0.001

−0.35

− 0.39 – − 0.30

< 0.001