Table 4 Comparison of serum macrophage migration inhibitory factor (MIF, pg/ml) according to different symptomatology among endometriotic participants

MIF (pg/ml)

Fertile (n = 21)

Infertile (n = 129)

p-value

Mean ± SD

1.05 ± 0.74

1.87 ± 1.54

0.019 (S)

Median (range)

1.20 (0.0–2.1)

1.60 (0.0–11.1)

95% CI

0.716–1.389

1.599–2.137

MIF (pg/ml)

Primary infertility (n = 72)

Secondary infertility (n = 57)

p-value

Mean ± SD

2.30 ± 1.72

1.32 ± 1.07

<  0.001 (S)

Median (range)

2.20 (0.0–11.1)

1.30 (0.0–7.0)

95% CI

1.9–2.709

1.034–1.602

MIF (pg/ml)

No Pain (n = 36)

Pain (n = 114)

p-value

Mean ± SD

0.871 ± 0.83

2.02 ± 1.54

<  0.001 (S)

Median (range)

0.90 (0.0–2.9)

1.70 (0.0–11.1)

95% CI

0.587–1.156

1.739–2.307