Table 4 Comparison of domain scores for Female Sexual Function Index (FSFI) questionnaire in the different stages of the study for the 4 types of LARCs evaluated

Desire

< 0.001

 Stage 1

4 ± 0.9

(3.9)

3.5 ± 1.1

(3.6)

3.6 ± 0.9

(3.6)

3.7 ± 1.4

(3.6)

 Stage 2

4.3 ± 0.9*

(4.2)

2.6 ± 0.9*^†£

(2.4)

4.2 ± 0.8^†

(4.2)

4.4 ± 1.2^£

(4.8)

Arousal

< 0.001

0.943

 Stage 1

4.8 ± 0.9

(4.8)

4.4 ± 0.9

(4.8)

4.8 ± 0.8

(5.1)

4.3 ± 1.2

(4.5)

 Stage 2

4.8 ± 0.9*

(4.8)

3.4 ± 1.3*^†£

(3.6)

5 ± 0.5^†

(5.1)

4.9 ± 0.8^£

(4.8)

Lubrification

< 0.001

 Stage 1

5 ± 0.9

(4.8)

4.7 ± 1.2

(4.8)

5.7 ± 0.5

(5.9)

4.6 ± 1.3

(4.8)

 Stage 2

5.2 ± 0.8*

(5.4)

3.5 ± 1.4 *^†£

(3.9)

5.7 ± 0.5^†

(6)

5.2 ± 1^£

(5.7)

Orgasm

0.002

 Stage 1

4.6 ± 1.4

(4.8)

4.3 ± 1.2

(4.4)

5 ± 0.8

(5.2)

4.2 ± 1.6

(4.4)

 Stage 2

4.6 ± 1.4*

(4.8)

3.3 ± 1.4*^†£

(3.2)

4.9 ± 0.8^†

(5.2)

4. 5 ± 1.5^£

(4.8)

Satisfaction

0.004

 Stage 1

5 ± 1.2 (5.4)

5.2 ± 0.9 (5.2)

5.4 ± 0.8 (5.6)

4.7 ± 1.2 (4.8)

 Stage 2

5.2 ± 0.9*

(5.4)

4.1 ± 1.3*^†£

(4.4)

5.2 ± 0.7^†

(5.2)

5 ± 0.9^£

(5.2)

Pain

0.001

 Stage 1

5.5 ± 0.7 (6)

5.1 ± 1.3 (6)

5.4 ± 1 (6)

4.9 ± 1.4 (5.2)

 Stage 2

5.5 ± 1*

(6)

4.3 ± 1.6*^†£

(4.8)

5.8 ± 0.5^†

(6)

5.3 ± 1^£

(6)

Total Score

 < 0.001

 Stage 1

28.9 ± 4.8

(28.7)

27.1 ± 5.3

(27.6)

30 ± 3

(30.8)

26.3 ± 6.7

(28.3)

 Stage 2

29.6 ± 4*

(29.8)

21.2 ± 6.9*^†£

(21.5)

30.7 ± 2.9^†

(31.1)

29.3 ± 4.8^£

(29.6)