Table 2 Patient characteristics and pathological findings of four women with contralateral SLN metastasis following bilateral IFL
Initial diagnosis | Smoker | Pathological results and disease chronology | |
|---|---|---|---|
1 | 2005 54 years’ old TZ = 2 cm TI = 5 mm BMI = 19.1 | Yes | SLNB showed left-sided metastasis 2 mm. IFL showed right-sided metastasis 2 mm. Subsequently, she received radiotherapy of both groins 2011: squamous cell laryngeal cancer (negative p16) 2014: squamous cell pulmonary cancer (negative p16) 2019: still alive with no signs of recurrence |
2 | 2015 56 years’ old TZ = 3,5 cm TI = 9 mm BMI = 29.8 | No | SLNB showed right-sided metastasis 9 mm with infiltration of blood vessel (V1) IFL showed left-sided metastasis 7 mm with extra capsular tumor cells Pelvic lymphadenectomy showed no metastasis. Subsequently, she received bilateral radiotherapy of her inguinal regions 2019: still alive with no signs of recurrence |
3 | 6/2016 67 years’ old TZ = 2,5 cm TI = 8 mm BMI = 28.8 | Yes | 2014: kidney transplantation (tacrolimus and mycophenolic acid) 6/2016: SLNB showed right-sided metastasis 3 mm. Complete IFL showed left-sided metastasis 3 mm Tacrolimus was changed into Everolimus. The patient received bilateral radiotherapy of her inguinal regions 8/2017: passed away due to lung metastasis of vulvar cancer |
4 | 2018 51 years’ old TZ = 1,6 cm TI = 2,3 mm BMI = 25.6 | Yes | SLNB showed right-sided metastasis 3 mm. IFL showed left-sided metastasis 8 mm. Pelvic lymphadenectomy showed no metastasis. Subsequently, she received bilateral radiotherapy of her inguinal regions 2019: recurrent vulvar cancer after 18 months (metastasis in fat tissue at mons pubis paramedian on the left side with infiltration into venous blood vessel). Surgery followed by radio chemotherapy was performed until December 2019 |