Skip to main content

Table 1 Association between clinicopathological factors and positive margins

From: Necessity for subsequent surgery in women of child-bearing age with positive margins after conization

Characteristics

Positive

(n = 321)

Negative

(n = 988)

Chi-squared

P value

Age (years)

 ≤ 35

23.02(102/443)

76.98(341/443)

0.812

0.368

 > 35

25.29(219/866)

74.71(647/866)

  

Gravidity

 ≤ 3

25.96(135/520)

74.04(385/520)

0.965

0.326

 > 3

23.57(186/789)

76.43(603/789)

  

Parity

 ≤ 2

23.84(201/843)

76.16(642/843)

0.590

0.442

 > 2

25.75(120/466)

74.24(346/466)

  

Cytology

Minor abnormalities

12.06(55/456)

87.94(401/456)

58.707

 < 0.001

Major abnormalities

31.18(266/853)

68.82((587/853)

  

High-risk HPV

Yes

31.42(268/853)

68.58(585/853)

62.912

 < 0.001

No

11.62(53/456)

88.38(403/456)

  

Transformation zone

I and II

11.08(106/957)

88.92(851/957)

347.6

 < 0.001

III

61.08(215/352)

38.92(137/352)

  

ECC

Positive

39.50(188/476)

60.50(288/476)

9.594

0.002

Negative

15.97(133/833)

84.03(700/833)

  

Quadrant involvement

Single

12.01(73/608)

87.99(535/608)

96.088

 < 0.001

Multiple

35.38(248/701)

64.62(453/701)

  

Glandular involvement

Yes

23.83(194/814)

76.17(620/814)

0.533

0.457

No

25.66(127/495)

74.34(368/495)

  

CIN grade

CIN2

26.42(79/299)

73.58(220/299)

0.755

0.385

CIN3

23.96(242/1010)

76.04(768/1010)

  
  1. Minor abnormalities included NILM (negative for intraepithelial lesion or malignancy), ASCUS (atypical squamous cells of undetermined significance), and LSIL (low-grade squamous intraepithelial lesion); major abnormalities included ASC-H (atypical squamous cells, cannot exclude high-grade squamous intraepithelial lesion) and HSIL (high-grade squamous intraepithelial lesion)