Table 1 Main characteristics of reported cases of hepatic malignant tumors arising from endometriosis
From: Malignant transformation of hepatic endometriosis: a case report and literature review
Author; year | Age (y) | Menopausal state/HRT | Prior surgery | History of endometriosis | Primary symptom/physical examination | Preoperative diagnosis/lesion size/location | Treatment | Histological subtype | Adjuvant therapy | Follow-up (y) |
|---|---|---|---|---|---|---|---|---|---|---|
Weinfeld [13] | 60 | Post/NA | HY + BSO; urinary bladder endometriosis resection | Yes | Right upper quadrant tenderness/NA | CT/3.1 cm/right lobe | Right diaphragmatic/perihepatic mass resection, left hepatectomy and cholecystectomy | Endometrioid adenosquamous carcinoma (moderately differentiated) | NA | NA |
N‘Senda [14] | 54 | Post/Yes | HY + BSO | Yes | Right-sided epigastric pain/hard palpable mass with tenderness in the right hypochondra | CT, MR/20 cm/right lobe | Right hepatectomy with adjacent diaphragm | Adenosarcoma | No | 2 |
Khan [15] | 59 | Post/NA | HY + BSO; laparotomy for intestinal endometrial stromal sarcoma (ESS) | Yes | Right upper quadrant abdominal pain/hepatomegaly | CT/NA/right lobe | Right hepatectomy | ESS (low-grade) | No | 4 |
Knowles [16] | 46 | Post/NA | HY + BSO + appendectomy | Yes | NA | NA | Right trisegmentectomy radical bile duct excision + lymphadenectomy | Endometrioid adenocarcinoma No | No | 1 |
Present case | 50 | Post/No | HY + BSO; cesarean section | Yes | Right upper quadrant abdominal pain/right upper quadrant tenderness | US, CT, MR/ 10 cm/right lobe | Right hepatectomy with infiltrating diaphragm resection | Endometrioid adenocarcinoma | Chemotherapy | Ongoing |