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Table 8 Accuracy of colposcopic Lugol’s staining bright yellow in predicting LSIL (LSIL and normal or benign) and Lugol’s staining mustard yellow in predicting HSIL+ (HSIL and carcinoma)

From: Clinical application of the 2011 IFCPC colposcope terminology

 

Sensitivity

(95% CI)

Specificity

(95% CI)

Positive predictive value (95% CI)

Negative predictive value (95% CI)

Youden index

Lugol’s staining bright yellow/LSIL

73.1%

(70.5–75.5%)

47.6%

(43.7–51.6%)

73.5%

(71.0–75.92%)

47.1%

(43.2–51.0%)

0.207

Lugol’s staining mustard/HSIL+

46.7%

(42.8–50.6%)

83.1%

(80.9–85.1%)

58.1%

(53.7–62.4%)

75.6%

(73.2–77.8%)

0.297

  1. LSIL, low-grade squamous intraepithelial lesion; HSIL, high-grade squamous intraepithelial lesion
  2. LSIL (LSIL and normal or benign); HSIL+ (HSIL and carcinoma)