Women in the 2019 hepatitis C cascade of care: findings from the British Columbia Hepatitis Testers cohort study

Pearce, Margo E.; Bartlett, Sofia R.; Yu, Amanda; Lamb, Jess; Reitz, Cheryl; Wong, Stanley; Alvarez, Maria; Binka, Mawuena; Velásquez Garcia, Héctor; Jeong, Dahn; Clementi, Emilia; Adu, Prince; Samji, Hasina; Wong, Jason; Buxton, Jane; Yoshida, Eric; Elwood, Chelsea; Sauve, Laura; Pick, Neora; Krajden, Mel; Janjua, Naveed Z.

doi:10.1186/s12905-021-01470-7

BMC Women's Health

Table 1 Demographic characteristics and comorbidity profile for women diagnosed with HCV in BC in 2019, stratified by care cascade stages

From: Women in the 2019 hepatitis C cascade of care: findings from the British Columbia Hepatitis Testers cohort study

Variable	Antibody Diagnosed		HCV RNA Tested		HCV RNA Positive		HCV Genotyped		HCV Treatment Initiated		SVR Achieved/Unknown		SVR Achieved
Variable	n	%	n	%	n	%	n	%	n	%	n	%	n	%
Total	19,522	100	16,797	100	11,075	100	10,007	100	6755	100	5683	100	4932	100
Birth Cohort
< 1945	974	4.99	786	4.68	570	5.15	505	5.05	322	4.77	270	4.75	228	4.62
1945–1964	10,046	51.46	8701	51.8	6028	54.43	5620	56.16	4288	63.48	3680	64.75	3279	66.48
1965–1974	4162	21.32	3492	20.79	2210	19.95	1975	19.74	1197	17.72	986	17.35	814	16.5
> 1974	4340	22.23	3818	22.73	2267	20.47	1907	19.06	948	14.03	747	13.14	611	12.39
Ethnicity
East Asian	1045	5.35	864	5.14	542	4.89	496	4.96	379	5.61	331	5.82	302	6.12
South Asian	872	4.47	803	4.78	549	4.96	521	5.21	395	5.85	338	5.95	263	5.33
Other BC Residents	17,605	90.2	15,130	90.1	9984	90.15	8990	89.84	5981	88.54	5014	88.22	4367	88.55
Material Deprivation Quintile
Q1 (most privileged)	2622	13.43	2294	13.66	1514	13.67	1390	13.89	953	14.11	797	14.02	698	14.15
Q2	2985	15.29	2602	15.49	1731	15.63	1597	15.96	1140	16.88	958	16.86	844	17.11
Q3	3557	18.22	3085	18.37	2058	18.58	1859	18.58	1337	19.79	1135	19.97	995	20.17
Q4	4407	22.57	3778	22.49	2511	22.67	2289	22.87	1569	23.23	1351	23.77	1155	23.42
Q5 (most deprived)	5391	27.61	4669	27.8	3033	27.39	2689	26.87	1662	24.6	1361	23.95	1168	23.68
Unknown	560	2.87	369	2.2	228	2.06	183	1.83	94	1.39	81	1.43	72	1.46
Social Deprivation Quintile
Q1 (most privileged)	2351	12.04	369	2.2	1369	12.36	1258	12.57	923	13.66	766	13.48	642	13.02
Q2	2337	11.97	2053	12.22	1320	11.92	1209	12.08	878	13	768	13.51	648	13.14
Q3	2992	15.33	2018	12.01	1749	15.79	1591	15.9	1113	16.48	943	16.59	838	16.99
Q4	4332	22.19	2599	15.47	2392	21.6	2175	21.73	1522	22.53	1269	22.33	1137	23.05
Q5 (most deprived)	6950	35.60	3717	22.13	4017	36.27	3591	35.88	2225	32.94	1856	32.66	1595	32.34
Unknown	560	2.87	6041	35.96	228	2.06	183	1.83	94	1.39	81	1.43	72	1.46
Urbanicity
Rural	2525	12.93	2222	13.23	1484	13.4	47	0.47	983	14.55	845	14.87	747	15.15
Urban	16683	85.46	14436	85.94	9511	85.88	1379	13.78	5766	85.36	4835	85.08	4182	84.79
Unknown	314	1.61	139	0.83	80	0.72	8581	85.75	6	0.09	3	0.05	3	0.06
History of Injection Drug Use
Yes	7265	37.21	6497	38.68	4210	38.01	3741	37.38	2122	31.41	1698	29.88	1412	28.63
No	12257	62.79	10300	61.32	6865	61.99	6266	62.62	4633	68.59	3985	70.12	3520	71.37
History of Opioid use*
Yes	4556	62.71	4154	63.94	2654	63.04	2375	63.49	1294	60.98	1021	60.13	843	59.7
No	2709	37.29	2343	3606	1556	36.96	1366	36.51	828	39.02	677	39.87	569	40.3
History of stimulant use*
Yes	4327	59.56	3938	60.61	2513	59.69	2238	59.82	1202	56.64	945	55.65	768	54.39
No	2938	40.44	2559	39.39	1697	40.31	1503	40.18	920	43.36	753	44.35	644	45.61
Problematic Alcohol Use
Yes	4952	25.37	4442	26.45	2797	25.26	2534	25.32	1549	22.93	1284	22.59	1084	21.98
No/Unknown	14570	74.63	12355	73.55	8278	74.74	7473	74.68	5206	77.07	4399	77.41	3848	78.02
Major Mental Health Diagnosis
Yes	7,379	37.8	6646	39.57	4331	39.11	3945	39.42	2572	38.08	2115	37.22	1804	36.58
No/Unknown	12,143	62.2	10,151	60.43	6744	60.89	6062	60.58	4183	61.92	3568	62.78	3128	63.42
HBV Coinfection
Yes	905	4.64	904	5.38	579	5.23	538	5.38	366	5.42	575	5.42	487	9.87
No/Unknown	18,617	95.36	15,893	94.62	10,496	94.77	9469	94.62	6389	94.58	5108	94.58	4445	90.13
HIV/AIDS Coinfection
Yes	565	2.89	904	5.38	475	4.29	448	4.48	281	4.16	233	4.1	204	4.14
No/Unknown	18,957	97.11	16,096	95.82	10,600	95.72	9559	95.53	6474	95.84	5450	95.9	4728	95.86
Cirrhosis
Yes	807	4.13	752	4.48	608	5.49	581	5.81	493	7.3	418	7.36	379	7.68
No/Unknown	18,715	95.87	16,045	95.52	10,467	94.51	9426	94.19	6262	92.7	5265	92.64	4553	92.32
Decompensated Cirrhosis
Yes	468	2.4	423	2.52	331	2.99	308	3.08	245	3.63	205	3.61	187	3.79
No/Unknown	19,054	97.6	16,374	97.48	10,744	97.01	9699	96.92	6510	96.37	5478	96.39	4745	96.21

*Includes only women with a history of injection drug use

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