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Table 3 Correlation between pathological types and HPV-DNA load

From: Significance of the viral load of high-risk HPV in the diagnosis and prediction of cervical lesions: a retrospective study

 

CIN I

CIN II

Univariable OR (95% CI)

P

Multivariable OR (95% CI)

P

Univariable OR (95% CI)

P

Multivariable OR (95% CI)

P

Age < 30 years

Ref

 

Ref

 

Ref

 

Ref

 

30–40 years

0.488 (0.187, 1.274)

0.143

0.51 (0.193, 1.345)

0.173

1.057 (0.343, 3.256)

0.923

1.173 (0.371, 3.71)

0.786

≥ 40 years

0.966 (0.432, 2.158)

0.932

0.931 (0.412, 2.107)

0.864

0.523 (0.16, 1.71)

0.283

0.483 (0.144, 1.62)

0.238

Low load

Ref

 

Ref

 

Ref

 

Ref

 

Moderate load

1.803 (0.879, 3.698)

0.108

1.815 (0.882, 3.737)

0.106

1.822 (0.664, 4.998)

0.244

1.804 (0.654, 4.976)

0.254

High load

3.905 (1.285, 11.869)

0.016

3.568 (1.164, 10.941)

0.026

5.857 (1.561, 21.973)

0.009

6.939 (1.793, 26.852)

0.005

 

CIN III

Cervical cancer

Univariable OR (95% CI)

P

Multivariable OR (95% CI)

P

Univariable OR (95% CI)

P

Multivariable OR (95% CI)

P

Age < 30 years

Ref

 

Ref

 

Ref

 

Ref

 

30–40 years

1.776 (0.572, 5.514)

0.321

1.92 (0.602, 6.124)

0.271

1.902 (0.188, 19.279)

0.586

2.122 (0.206, 21.864)

0.527

≥ 40 years

2.421 (0.838, 6.99)

0.102

2.275 (0.768, 6.734)

0.138

7.172 (0.903, 56.986)

0.062

6.599 (0.818, 53.229)

0.076

Low load

Ref

 

Ref

 

Ref

 

Ref

 

Moderate load

2.847 (1.324, 6.121)

0.007

2.852 (1.322, 6.152)

0.008

2.278 (0.744, 6.971)

0.149

2.308 (0.744, 7.159)

0.148

High load

7.321 (2.426, 22.093)

< 0.001

7.052 (2.304, 21.586)

0.001

10.041 (2.64, 38.19)

0.001

8.266 (2.12, 32.233)

0.002

  1. CIN Cervical intraepithelial neoplasia, OR odds ratio, CI confidence interval