Table 3 Association between fatal stroke occurrence and age at menopause in the GBCS

Total cohort

940

2805

6600

2928

3231

No. of deaths

26 (0.028)

42 (0.015)

88 (0.013)

31 (0.010)

35 (0.010)

Model 1

(HR, 95% CI)

2.58 (1.53–4.35), P < 0.001

1.40 (0.88–2.23), P = 0.16

1.25 (0.83–1.88), P = 0.29

1.00

0.98 (0.61–1.59), P = 0.94

Model 2

(HR, 95% CI)

1.64 (0.97–2.78), P = 0.06

1.09 (0.69–1.74), P = 0.71

1.10 (0.73–1.65), P = 0.66

1.00

0.99 (0.61–1.61), P = 0.96

Born < 1940^$ cohort

413

981

1996

752

796

No. of deaths

22 (0.053)

36 (0.037)

62 (0.031)

18 (0.024)

26 (0.033)

Model 1

(HR, 95% CI)

2.30 (1.23–4.28), P = 0.009

1.52 (0.86–2.67), P = 0.15

1.29 (0.77–2.18), P = 0.34

1.00

1.33 (0.73–2.42), P = 0.35

Model 2

(HR, 95% CI)

1.97 (1.05–3.69), P = 0.03

1.43 (0.81–2.52), P = 0.22

1.25 (0.74–2.11), P = 0.41

1.00

1.35 (0.74–2.47), P = 0.33

Born ≥ 1940^& cohort

527

1824

4604

2176

2435

No. of deaths

4 (0.008)

6 (0.003)

26 (0.006)

13 (0.006)

9 (0.004)

Model 1

(HR, 95% CI)

1.24 (0.41–3.81), P = 0.71

0.55 (0.21–1.46), P = 0.23

0.94 (0.48–1.83), P = 0.86

1.00

0.59 (0.25–1.38), P = 0.22

Model 2

(HR, 95% CI)

1.00 (0.32–3.08), P = 0.99

0.52 (0.20–1.37), P = 0.19

0.92 (0.47–1.79), P = 0.80

1.00

0.54 (0.23–1.27), P = 0.16