Table 2 Histopathologic diagnoses in the study women stratified by menopausal status
Type of lesion | Premenopausal (n = 403 women) | Postmenopausal (n = 617 women) | p value |
|---|---|---|---|
Benign | 399 (90.01%) | 587 (95.14%) | O.R. [95% C.I.] = 5.098 [1.782–14.582], P < 0.005 |
Premalignant/malignant | 4 (0.99%) | 30 (4.46%) | |
Detail of benign lesions | |||
Endometrial cystic-glandular atrophy | 2 (0.50%) | 10 (1.62%) | χ2 = 2.65, [95% C.I.: − 0.37 to 2.50] P = 0.10, NS |
Endometrium with dysfunctional proliferative disorders | 19 (4.71%) | 3 (0.49%) | χ2 = 20.54, [95% C.I.: 2.30–6.77] P < 0.0001 |
Normal endometrium | 51 (12.66%) | 4 (0.65%) | χ2 = 68.82, [95% C.I.: 8.94–15.63] P < 0.0001 |
Endometrial polyp | 312 (77.42%) | 540 (87.52%) | χ2 = 18.05, [95% C.I.: 5.34–-15.03] P < 0.0001 |
Other benign lesions* | 9 (2.23%) | 20 (3.24%) | χ2 = 0.90, [95% C.I.: − 1.24 to 3.01] P = 0.34, NS |
Simple glandular hyperplasia | 6 (1.48%) | 9 (1.46%) | χ2 = 0.001, [95% C.I.: − 1.49 to 1.87] P = 0.97, NS |
Complex glandular hyperplasia without atypia | 0 | 1 (0.16%) | χ2 = 0.63, [95% C.I.: − 0.79 to 0.90] P = 0.42, NS |
Detail of premalignant/malignant lesions | |||
Complex endometrial hyperplasia with atypia | 4 (0.99%) | 18 (2.91%) | χ2 = 4.26, [95% C.I.: 0.05–3.67] P < 0.05 |
Endometrial cancer | 0 | 12 (1.94%) | χ2 = 7.90, [95% C.I.: 0.68–3.36] P < 0.005 |