Baseline | 2 months | 6 months | 12 months | 24 months | 36 months | ||||||||
---|---|---|---|---|---|---|---|---|---|---|---|---|---|
HPV type | Serological outcome | HPV + n (%) | HPV − n (%) | HPV + n (%) | HPV − n (%) | HPV + n (%) | HPV − n (%) | HPV + n (%) | HPV − n (%) | HPV + n (%) | HPV − n (%) | HPV + n (%) | HPV − n (%) |
Always Seronegative | 12(32.4) | 56 (29.6) | 17(34.7) | 51 (29.5) | 16(30.2) | 51 (30.2) | 12(27.3) | 56 (30.6) | 14(27.5) | 51 (32.7) | 10(31.3) | 53 (31.0) | |
HPV6 | Seroconversion | 1 (2.7) | 4 (2.1) | 0 (0.0) | 5 (2.9) | 1 (1.9) | 4 (2.4) | 1 (2.3) | 4 (2.2) | 1 (2.0) | 3 (1.9) | 0 (0.0) | 3 (1.8) |
Persistent Seropositivity | 24(64.9) | 129 (68.3) | 32 (65.3) | 117 (67.6) | 36 (67.9) | 114 (67.5) | 31 (70.5) | 123 (67.2) | 36 (70.6) | 102 (65.4) | 22 (68.8) | 115 (67.3) | |
Always Seronegative | 28 (80.0) | 158 (81.4) | 39(83.0) | 146 (81.6) | 46 (85.2) | 137 (80.1) | 33 (80.5) | 153 (81.4) | 42 (89.4) | 137 (83.0) | 26 (81.3) | 148 (84.1) | |
HPV11 | Seroconversion | 2 (5.7) | 2 (1.0) | 3 (6.4) | 1 (0.6) | 1 (1.9) | 3 (1.8) | 1 (2.4) | 3 (1.6) | 1 (2.1) | 0 (0.0) | 0 (0.0) | 2 (1.1) |
Persistent Seropositivity | 5 (14.3) | 34 (17.5) | 5 (10.6) | 32(17.9) | 7 (13.0) | 31 (18.1) | 7 (17.1) | 32 (17.0) | 4 (8.5) | 28 (17.0) | 6 (18.8) | 26 (14.8) | |
Always Seronegative | 26 (70.3) | 122 (64.6) | 30 (62.5) | 116 (66.7) | 28 (62.2) | 117 (66.1) | 24 (58.5) | 124 (68.9) | 26 (59.1) | 115 (70.1) | 19 (59.4) | 118 (69.0) | |
HPV16 | Seroconversion | 1 (2.7) | 11 (5.8) | 2 (4.2) | 9 (5.2) | 2 (4.4) | 10 (5.6) | 2 (4.9) | 10 (5.6) | 3 (6.8) | 6 (3.7) | 1 (3.1) | 9 (5.3) |
Persistent Seropositivity | 10 (27.0) | 56 (29.6) | 16 (33.3) | 49 (28.2) | 15 (33.3) | 50 (28.2) | 15 (36.6) | 51 (28.3) | 15 (34.1) | 43 (26.2) | 12 (37.5) | 44 (25.7) | |
Always Seronegative | 33 (78.6) | 155 (74.5) | 42 (79.2) | 144 (75.0) | 46 (79.3) | 140 (74.5) | 33 (80.5) | 156 (74.3) | 41 (75.9) | 137 (77.0) | 29 (80.6) | 144 (75.0) | |
HPV18 | Seroconversion | 3 (7.1) | 8 (3.8) | 2 (3.8) | 8 (4.2) | 1 (1.7) | 10 (5.3) | 0 (0.0) | 11 (5.2) | 3 (5.6) | 8 (4.5) | 0 (0.0) | 11 (5.7) |
Persistent Seropositivity | 6 (14.3) | 45 (21.6) | 9 (17.0) | 4 (20.8) | 11 (19.0) | 38 (20.2) | 8 (19.5) | 43 (20.5) | 10 (18.5) | 33 (18.5) | 7 (19.4) | 37 (19.3) | |
Always Seronegative | 42 (93.3) | 199 (90.5) | 53 (93.0) | 184 (90.6) | 58 (89.2) | 181 (91.9) | 47 (92.2) | 195 (90.7) | 55 (93.2) | 173 (92.0) | 35 (89.7) | 187 (92.1) | |
HPV45 | Seroconversion | 1 (2.2) | 3 (1.4) | 1 (1.8) | 3 (1.5) | 2 (3.1) | 2 (1.0) | 2 (3.9) | 2 (0.9) | 2 (3.4) | 1 (0.5) | 1 (2.6) | 2 (1.0) |
Persistent Seropositivity | 2 (4.4) | 18 (8.2) | 3 (5.3) | 16 (7.9) | 5 (7.7) | 14 (7.1) | 2 (3.9) | 18 (8.4) | 2 (3.4) | 14 (7.4) | 3 (7.7) | 14 (6.9) |