Molecular phenotypes and clinical characterization of familial hereditary breast cancer among half and full sisters

Table 8 Comparison of enzyme-labeled staining for CK5/6, E-cad, P63 and P120 across subgroups

Variable	NHBC	HBC			Total
Variable	NHBC	CHBC	NCHBC	CHBC + NCHBC	Total
Expression of CK5/6, n	152	18	20	38	190
(−)	123	13	18	31	154
(+)	29	5	2	7	36
	X² = 0.11 P > 0.05	X² = 0.76 *P > 0.05	X² = 0.47 **P > 0.05	X² = 0.99 ^#P > 0.05
Expression of E-cad, n
(−)	4	4	3	7	11
(+)	148	14	17	31	179
	X² = 11.15 P < 0.005	X² = 9.75 *P < 0.005	X² = 4.12 **P < 0.05	X² = 0.27 ^#P > 0.05
Expression of P63, n
(−)	125	11	17	28	153
(+)	27	7	3	10	37
	X² = 1.42 P > 0.05	X² = 4.49 *P < 0.05	X² = 0.00 **P > 0.05	X² = 1.69 ^#P > 0.05
Expression of P120, n
(−)	5	1	0	1	6
(+)	147	17	20	37	184
	X² = 0.11 P > 0.05	X² = 0.33 *P > 0.05

HBC hereditary breast cancer, NHBC non-hereditary breast cancer, CHBC contemporaneous hereditary breast cancer, NCHBC non-contemporaneous hereditary breast cancer
P = NHBC versus HBC, *P = NHBC versus CHBC, **P = NHBC versus NCHBC, ^#P = CHBC versus NCHBC

ISSN: 1472-6874