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Table 2 The comparison between SLE patients with and without sexual dysfunction concerning the demographic and clinic characteristics, and the different indices

From: Fatigue have impact on the sexual problems in Chinese females with systemic lupus erythematosus

Variables

With sexual dysfunction (n = 101)

Without sexual dysfunction (n = 27)

t/F/x2

P

Age (years)

40.90 ± 13.50

36.37 ± 6.84

2.44

0.018*

BMI (kg/m2)

23.14 ± 4.28

23.02 ± 3.69

0.13

0.896

Marital status

  

10.94

0.001**

 Single/divorced/widowed

30 (29.7)

1 (3.7)

  

 Married

70 (70.3)

26 (96.3)

  

Having child (yes)

68 (67.3)

24 (88.9)

4.90

0.027*

Education

  

0.01

0.973

 Primary and below

20 (19.8)

4 (14.8)

  

 Secondary

29 (28.7)

9 (33.3)

  

 Graduate and above

52 (51.5)

14 (51.9)

  

Employment status

  

1.17

0.279

 Unemployed

53 (52.5)

11 (40.7)

  

 Employed

48 (47.5)

16 (59.3)

  

Income/person/month

  

0.78

0.379

 ≤ 1000 Yuan

2 (2.0)

0 (0)

  

 1000–3000 yuan

23 (22.8)

5 (18.5)

  

 3000–5000 yuan

28 (27.7)

7 (25.9)

  

 ≥ 5000 yuan

48 (47.5)

15 (55.6)

  

Health insurance (yes)

86 (85.1)

23 (85.2)

0.01

0.996

Religious beliefs (yes)

13 (12.9)

4 (14.8)

0.07

0.792

History of hospitalization (yes)

81 (80.2)

20 (74.1)

0.48

0.488

History of family (yes)

14 (13.9)

1 (3.7)

2.13

0.145

Comorbid condition (yes)

62 (61.4)

12 (44.4)

2.51

0.113

Residence

  

0.01

0.974

 Urban

90 (89.1)

24 (88.9)

  

 Rural

11 (10.9)

3 (11.1)

  

SLE disease duration (years)

6.39 ± 7.22

3.80 ± 2.77

2.89

0.005**

VAS pain (range 0–10)

2.00 ± 1.50

1.67 ± 1.14

1.07

0.286

SLEDAI

6.28 ± 7.88

2.78 ± 3.64

3.33

0.001**

DMARDs usage (yes)

73 (72.3)

26 (96.3)

7.01

0.008**

Corticosteroid usage (yes)

84 (83.2)

23 (85.2)

0.01

0.802

Biologics usage (yes)

18 (17.8)

8 (29.6)

1.84

0.176

Depression (PHQ9)

5.27 ± 4.88

2.81 ± 4.54

2.35

0.020*

Fatigue (MFI)

    

 General fatigue

12.12 ± 3.09

10.67 ± 3.36

2.13

0.035*

 Physical fatigue

12.37 ± 3.53

10.67 ± 2.98

2.29

0.024*

 Mental fatigue

10.42 ± 3.67

8.12 ± 3.54

2.83

0.005**

 Reduced motivation

9.35 ± 2.87

8.56 ± 3.30

1.23

0.220

 Reduced activity

11.67 ± 3.03

9.96 ± 4.00

2.01

0.046*

 Total score

56.43 ± 13.05

48.04 ± 13.51

2.95

0.004**

Quality of life (SF-12)

    

 PCS

44.11 ± 8.85

47.48 ± 7.91

− 1.80

0.075

 MCS

45.96 ± 5.77

46.39 ± 4.82

− 0.36

0.720

 Total score

90.06 ± 9.29

93.87 ± 8.07

− 1.94

0.046*

  1. Data are presented as mean ± SD or number (%)
  2. SLE Systemic Lupus Erythematosus, BMI Body Mass Index, VAS Visual Analog Scale, SLEDAI Systemic Lupus Erythematosus Disease Activity Index, DMARDs Disease-Modifying Anti-rheumatic Drugs, PDD Perceived Devaluation-Discrimination, PHQ-9 Patient Health Questionnaire-9, MFI Multiple Fatigue Inventory, SF-12 Short Form 12 health survey, PCS physical components summary, MCS mental components summary
  3. *P < 0.05; **P < 0.01