From: Reassessment of intensive surveillance practices adopted for endometrial cancer survivors
 | Univariate | Multivariate | ||
---|---|---|---|---|
 | Hazard ratio [95% CI] | p-value* | Hazard ratio [95% CI] | p-value* |
FIGO stage | Â | Â | Â | Â |
 I | ref |  |  | |
 II | 1.736 [0.498–6.048] | 0.387 |  |  |
 III | 1.271 [0.678–2.385] | 0.454 |  |  |
 IV | 1.767 [0.845–3.691] | 0.130 |  |  |
Histology | Â | Â | Â | Â |
 Endometrioid G1/G2 | ref |  |  | |
 Endometrioid G3 | 1.151 [0.550–2.408] | 0.708 |  |  |
 Serous | 0.906 [0.314–2.612] | 0.885 |  |  |
 Other | 1.792 [0.791–4.055] | 0.162 |  |  |
Initial treatment | Â | Â | Â | Â |
 ATH + BSO | ref |  |  | |
 ATH + BSO + PLA biopsy | 0.678 [0.280–1.638] | 0.388 |  |  |
 ATH + BSO + PLA | 0.659 [0.327–1.329] | 0.244 |  |  |
 ATH + BSO + PLA + PAN | 0.596 [0.275–1.288] | 0.188 |  |  |
 NAC + ATH + BSO | 0.830 [0.235–2.928] | 0.772 |  |  |
Time to recurrence | 0.999 [0.0998–1.000] | 0.008 |  |  |
Recurrence site | Â | Â | Â | Â |
 Local | ref | ref | ||
 Pelvic and para-aortic LN | 5.836 [2.143–15.892] | 0.001 | 5.311 [1.866–15.114] | 0.002 |
 Peritoneal dissemination | 3.088 [1.061–8.984] | 0.039 | 2.699 [0.910–8.004] | 0.073 |
 Distant metastasis | 4.100 [1.6961–9.911] | 0.002 | 3.876 [1.542–9.743] | 0.004 |
Diagnosis method at recurrence | Â | Â | Â | Â |
 Outpatient exam | ref |  |  | |
 Symptom | 1.042 [0.429–2.529] | 0.928 |  |  |
 Tumor marker | 1.830 [0.797–4.353] | 0.172 |  |  |
 Imaging analysis | 1.385 [0.640–2.999] | 0.409 |  |  |