|  < 40Y |  > 40Y | p |
---|---|---|---|
Number of cycles | 265 | 486 | Â |
Age (years), mean ± SD | 35.81 ± 3.86 | 42.70 ± 1.42 |  < 0.001 |
BMI (kg/m2), mean ± SD | 25.64 ± 6.11 | 26.31 ± 6.19 | 0.1789 |
Gravity, mean ± SD | 1.15 ± 1.49 | 1.27 ± 1.53 | 0.2991 |
Parity, mean ± SD | 0.44 ± 0.78 | 0.46 ± 0.64 | 0.7150 |
Protocol | Â | Â | 0.0391 |
  Antagonist, n (%) | 184 (69.4%) | 352 (72.4%) |  |
  MNC, n (%) | 67 (25.3%) | 88 (18.1%) |  |
  Short agonist, n (%) | 9 (3.4%) | 27 (5.6%) |  |
  Long agonist, n (%) | 5 (1.9%) | 19 (3.9%) |  |
Day 3 FSH levels (IU/L), mean ± SD | 12.97 ± 8.97 | 13.60 ± 11.38 | 0.5261 |
Duration of stimulation (days), mean ± SD | 8.58 ± 3.76 | 9.42 ± 3.65 | 0.003 |
Total dose of gonadotropins (IU), mean ± SD | 3307.3 ± 2245.6 | 4332.3 ± 2409.9 |  < 0.001 |
No. of follicles ≥ 15 mm, mean ± SD | 1.68 ± 0.76 | 1.66 ± 0.74 | 0.7976 |
Leading follicle size (mm), mean ± SD | 18.53 ± 2.17 | 18.10 ± 2.04 | 0.006 |
E2 level at the trigger day (pmol/L), mean ± SD | 1750.3 ± 1115.5 | 1769.4 ± 939.6 | 0.802 |
Trigger | Â | Â | 0.403 |
  hCG, n (%) | 192 (72.5%) | 338 (69.6%) |  |
  Dual trigger, n (%) | 73 (27.5%) | 148 (30.4%) |  |
Progesterone levels at the trigger day (nmol/L), mean ± SD | 1.43 ± 1.04 | 1.50 ± 1.21 | 0.435 |
No. of retrieved oocytes, mean ± SD | 1.55 ± 0.99 | 1.54 ± 0.97 | 0.9217 |
Cycles with no oocytes, n (%) | 41 (15.47%) | 78 (16.05%) | 0.852 |
Top quality embryos, mean ± SD | 0.37 ± 0.59 | 0.33 ± 0.55 | 0.391 |
Fertilization rate, mean ± SD | 0.63 ± 0.40 | 0.62 ± 0.4 | 0.6315 |
Pregnancy rate per cycle, n (%) | 26/265(9.81%) | 22/486 (4.53%) | 0.004 |
Live birth per cycle, n (%) | 18/265 (6.79%) | 10/486 (2.06%) | 0.001 |