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Table 1 Patients’ characteristics and cycle outcomes by woman’s age group

From: Predicting IVF outcome in poor ovarian responders

 

 < 40Y

 > 40Y

p

Number of cycles

265

486

 

Age (years), mean ± SD

35.81 ± 3.86

42.70 ± 1.42

 < 0.001

BMI (kg/m2), mean ± SD

25.64 ± 6.11

26.31 ± 6.19

0.1789

Gravity, mean ± SD

1.15 ± 1.49

1.27 ± 1.53

0.2991

Parity, mean ± SD

0.44 ± 0.78

0.46 ± 0.64

0.7150

Protocol

  

0.0391

  Antagonist, n (%)

184 (69.4%)

352 (72.4%)

 

  MNC, n (%)

67 (25.3%)

88 (18.1%)

 

  Short agonist, n (%)

9 (3.4%)

27 (5.6%)

 

  Long agonist, n (%)

5 (1.9%)

19 (3.9%)

 

Day 3 FSH levels (IU/L), mean ± SD

12.97 ± 8.97

13.60 ± 11.38

0.5261

Duration of stimulation (days), mean ± SD

8.58 ± 3.76

9.42 ± 3.65

0.003

Total dose of gonadotropins (IU), mean ± SD

3307.3 ± 2245.6

4332.3 ± 2409.9

 < 0.001

No. of follicles ≥ 15 mm, mean ± SD

1.68 ± 0.76

1.66 ± 0.74

0.7976

Leading follicle size (mm), mean ± SD

18.53 ± 2.17

18.10 ± 2.04

0.006

E2 level at the trigger day (pmol/L), mean ± SD

1750.3 ± 1115.5

1769.4 ± 939.6

0.802

Trigger

  

0.403

  hCG, n (%)

192 (72.5%)

338 (69.6%)

 

  Dual trigger, n (%)

73 (27.5%)

148 (30.4%)

 

Progesterone levels at the trigger day (nmol/L), mean ± SD

1.43 ± 1.04

1.50 ± 1.21

0.435

No. of retrieved oocytes, mean ± SD

1.55 ± 0.99

1.54 ± 0.97

0.9217

Cycles with no oocytes, n (%)

41 (15.47%)

78 (16.05%)

0.852

Top quality embryos, mean ± SD

0.37 ± 0.59

0.33 ± 0.55

0.391

Fertilization rate, mean ± SD

0.63 ± 0.40

0.62 ± 0.4

0.6315

Pregnancy rate per cycle, n (%)

26/265(9.81%)

22/486 (4.53%)

0.004

Live birth per cycle, n (%)

18/265 (6.79%)

10/486 (2.06%)

0.001

  1. BMI, body mass index, MNC, modified natural cycle