Table 2 Univariate Cox analysis in 345 AC patients

Age

0.009

0.047

 Mean ± SD

1.044 [1.011, 1.079]

2.152 [1.011, 4.58]

FIGO stage (%)

 < 0.001

0.003

 Stage 1

1

1

 Stage 2

3.98 [1.839, 8.611]

3.754 [1.584, 8.899]

Silva (%)

 Type A

1

1

 Type B

3.282 [0.341, 31.556]

3.279 [0.341, 31.531]

 Type C

18.936 [2.576, 139.2]

15.472 [2.089, 114.607]

Comorbidity (%)

0.289

0.373

 No

1

1

 Yes

1.616 [0.665, 3.928]

1.555 [0.589, 4.108]

Adjuvant treatment (%)

0.012

0.026

 No

1

1

 Yes

3.11 [1.28, 7.557]

3.017 [1.142, 7.967]

LEEP (%)

0.703

0.443

 No

1

1

 Yes

0.679 [0.093, 4.974]

0.046 [0, 119.3]

Surgical approach (%)

0.019

0.008

 Laparoscopy

1

1

 Laparotomy

2.623 [1.169, 5.89]

3.097 [1.344, 7.134]

Surgical duration, min (%)

0.914

0.226

  ≤ 200

1

1

  > 200

0.962 [0.478, 1.936]

0.616 [0.281, 1.35]

Blood loss, ml (%)

0.975

0.996

  ≤ 200

1

1

  > 200

0.989 [0.49, 1.995]

0.998 [0.465, 2.14]

Transfusion (%)

0.015

0.005

 No

1

3.66 [1.475, 9.084]

 Yes

3.024 [1.241, 7.37]

LN metastasis (%)

 < 0.001

 < 0.001

 No

1

1

 Yes

5.94 [2.969, 11.885]

8.349 [3.873, 17.997]

LN metastasis site (%)

 < 0.001

 < 0.001

 No

1

1

 Pelvic

2.956 [1.156, 7.557]

4.254 [1.573, 11.506]

 Common iliac

15.596 [6.873, 35.388]

20.178 [8.35, 48.762]

 Para-aortic

12.111 [1.587, 92.455]

17.452 [2.178, 139.82]

Surgical margin (%)

0.001

 < 0.001

 No

1

1

 Yes

5.307 [2.041, 13.798]

7.697 [3.105, 19.078]

Parametrial invasion (%)

 < 0.001

 < 0.001

 No

1

1

 Yes

5.516 [2.383, 12.768]

6.493 [2.743, 15.369]

Tumor size, cm (%)

0.001

0.002

  ≤ 2

2.198 [0.895, 5.396]

1

 (2,4)

5.834 [2.217, 15.354]

1.556 [0.603, 4.016]

  > 4

5.355 [1.991, 14.406]

LVSI (%)

 No

1

14.675 [4.176, 51.57]

 Mild

13.207 [4.411, 39.544]

25.267 [7.034, 90.757]

 Substantial

21.02[6.768,65.285]

DSI (%)

  < 2/3

1

1

  ≥ 2/3

20.369 [4.868, 85.236]

7.463 [2.581, 21.581]

PNI (%)

 No

1

1

 Yes

3.955 [1.519, 10.293]

4.898 [1.848, 12.981]