Table 1 Reported cases of hemoperitoneum in patients with bleeding disorders
From: Corpus luteum hemorrhage with acquired hemophilia A: a case report and literature review
References | Diagnosis | Details | Management |
|---|---|---|---|
Bottini et al. [10] | Type 3 VWD | Two patients had hemorrhagic CL | One had surgery (wedge resection of ovary), another treated with conservative management. Recurrence prevented by OC |
Bottini et al. [10] | Afibrinogenemia | 22 Years old. Three episodes of hemorrhagic CL | Each episode required surgery. Recurrence prevented by OC |
Meschengieser et al. [9] | Combined mild VWD and mild storage pool defect | 19 Years old. Three episodes of bleeding over 13 years | Surgery (wedge resection of ovary) |
Ghosh et al. [8] | Type 3 VWD | 29 Years old. Three episodes. Two of three needing resuscitation | Conservative management. Recurrence prevented by OC and TA |
Gomez et al. [7] | Type 3 VWD | 22 Years old. Hemoperitoneum from rupture of ovarian cyst | Exploratory laparotomy (oophorectomy) |
Greer et al. [6] | Type 2 VWD mild | Hemorrhagic corpus luteum and broad ligament hematoma | Salpingo-oophorectomy while conservative management with cryoprecipitate had no effect |
Jarvis et al. [5] | Type 1 VWD | Recurrent corpus hemorrhagicum two episodes | Blood support and exploratory laparotomy Conservative management No recurrence for 4 years by OC |
Terzic et al. [4] | VWD severe | Massive hematoperitoneum caused by ovulation. Had right adnexectomy due to hemorrhagic CL four months prior | Conservative management by blood product and factor concentrate support. Recurrence prevented by OC |
Cetinkaya et al. [13] | Congenital afibrinogenemia | 24 Years old. Two episodes of massive intraabdominal bleeding due to ovulation | Exploratory laparotomy and excision of the ruptured follicle at first episode. Conservative management with blood support at second episode |
Castaman et al. [12] | Congenital afibrinogenemia | 24 Years old. Two episodes of hemoperitoneum during ovulation | Both episodes required operative intervention and replacement therapy. No recurrence over 5 years by OC |
Koussi et al. [11] | Congenital afibrinogenemia | 14 Years old. Developed intra-abdominal bleeding due to the rupture of an ovarian cyst | Replacement therapy (red cells and cryoprecipitate) |
O’Brien et al. [15] | Hemophilia A | 18 Years old. Hemorrhagic ovarian cyst | Conservative therapy (factor VIII therapy) |
Dafapoulos et al. [19] | Factor X deficiency | 24 Years old. Two episodes of hemoperitoneum from luteal cyst rupture | Both episodes removed the ruptured cyst by surgery |
Khamashta et al. [18] | Antiphospholipid antibody syndrome | Severe ovarian hemorrhage during warfarin treatment | |
Yamakami et al. [17] | Antiphospholipid syndrome | Three patients had severe hemorrhagic CL while receiving warfarin treatment | All of them required prompt blood transfusion and emergency surgery |
Castellino et al. [16] | Antiphospholipid syndrome | Two episodes of ovarian hemorrhage while receiving oral anticoagulation | One required oophorectomy |
Singh et al. [20] | Factor XIII deficiency | 13 Years old. CL hemorrhage | Laparoscopic surgery with blood support |
Badyal et al. [21] | Factor V deficiency | 19 Years old. Recurrent CL hemorrhage three episodes | Each episode required surgery and blood support |
Schneider et al. [14] | Congenital afibrinogenemia | 22 Years old. Bleeding from a ruptured CL | Oophorectomy was performed with blood support |