Table 6 Impact of different medications on QLQ of breast cancer patients based on EORTC QLQ C-30 scales

Global health status

42.60 ± 2.5

64.76 ± 2.5

67.23 ± 7.1

0.000***

Functional scales

 Physical functioning

71.17 ± 2.4

73.25 ± 2.3

80.95 ± 4.9

0.32

 Role functioning

48.89 ± 3.9

75.93 ± 3.3

88.10 ± 7.0

0.000***

 Emotional functioning

54.36 ± 3.9

73.46 ± 3.5

69.06 ± 8.3

0.002**

 Cognitive functioning

82.70 ± 2.6

77.99 ± 2.6

80.96 ± 7.5

0.476

 Social functioning

46.67 ± 3.1

68.73 ± 3.3

78.57 ± 7.8  

0.000***

Symptom scales

 Fatigue

52.39 ± 3.3

24.41 ± 2.7

15.87 ± 7.0

0.000***

 Nausea/vomiting

53.65 ± 3.3

9.88 ± 2.3

16.67 ± 8.5

0.000***

 Pain

46.99 ± 3.4

24.06 ± 3.0

21.42 ± 7.8

0.000***

 Dyspnea

15.56 ± 2.8

12.75 ± 2.6

7.14 ± 5.1

0.484

 Insomnia

65.08 ± 4.0

39.51 ± 4.7

30.96 ± 10.7

0.000***

 Appetite loss

52.71 ± 4.1

21.40 ± 3.8

11.90 ± 7.4

0.000***

 Constipation

23.49 ± 3.9

17.69 ± 3.7

16.66 ± 8.3

0.527

 Diarrhea

40.00 ± 4.1

9.46 ± 2.4

33.34 ± 12.5

0.000***

Financial difficulties

70.16 ± 3.9

55.14 ± 4.6

64.29 ± 10.7

0.049*