Table 1 Characteristics of the selected studies
Author(year) | Deign | Participants | Intervention | Adherence | biomarkers | Other variables |
|---|---|---|---|---|---|---|
Irwin, etc.* (2009) [48] | Two-arm RCT. AT;UC | N = 75, stage I-IIIA BCS, AT mean age: 56.4 ± 9.5 | AT, 24wks, 5 d/wk, 150 min/wk | IGF-1,IGF-3 | Insulin, etc | |
Lisa, etc. (2011) [33] | Two-arm RCT.TCC; SST | N = 21, I-IIIB BCS, TCC mean age: 54.33 ± 10.64 | TCC, 12 wks, 3 d/wk,60 min | 72% | IL-6 IGF-1 IGFBP-3 | HRQOL, etc |
Gomez, etc.(2011) [41] | Two-arm RCT.AT + RT;UC | N = 16, stage I-II BCS, mean age:50 ± 5 | AT + RT 8 wks, 3 d/wk, 90 min, supervised | 91% | IL-1, IL-10 IL-1β IL-6, IL-10/TNF-α TNF-α, | VO2max weight, etc |
Rogers, etc. (2012) [43] | Two-arm RCT.AT + RT;UC | N = 28, I-IIIA BCS, mean age: 56 ± 10.5 | AT + RT, 12 wks, 2 d/wk, 150 min/wk supervised | IL-10, IL-6, Il-1β, IL-6/IL-10,TNF-α/IL-10 | BMI, Fatigue, etc | |
Jones, etc.* (2012) [42] | Two-arm RCT AT;UC | N = 75, stage I-IIIA BCS, AT mean age: 56.4 ± 9.5 | AT, 24 wks, 5 d/wk, 150 min/wk | CRP、IL-6、TNF-α | BMI, etc | |
Bower, etc. (2013) [44] | Two-arm RCT. yoga; HE | N = 31, stage I-II BCS; mean age: 54 ± 5.7 | Yoga,12w ks, 2 d/wk, 90 min, supervised | 78% | IL-6, CRP | Fatigue, depression, etc |
Karimi, etc. (2015) [38] | Four-arm RCT. exercise; placebo; GS; exercise + GS | N = 40, stage I-II BCS, exercise mean age: 47.3 ± 8.1 | Water-Based Exercise, 6 wks, 4 d/wk, 40–80 min | IL-10, hs-CRP | Insulin, etc | |
Christina, etc. (2017) [45] | Two-arm RCT.AT + RT; delayed intervention control | N = 20, stage I-III BCS, AT + RT mean age: 53.0 ± 10 | AT + RT, 16 wks, 3 d/wk 80 min, supervised | 97% | CRP, IL-6 | Body composition, etc |
Christina, etc. (2018) [46] | Two-arm RCT. AT + RT; UC | N = 100, stage BCS, mean age: 53.5 ± 10.4 | AT + RT, 16 wks, 3 d/wk AT:150 min/wk, supervised | 95% | IGF-1, CRP, IL-6, TNF-α | Weight, BMI, etc |
Kim, etc. (2019) [47] | Two-arm RCT. exercise; no exercise | N = 50, stage I-IIIA BCS, exercise mean age: 49.95 ± 8.12 | stretching and resistance exercise, 12 wks, 1d/wk | 90% | IL-6,TNF-α | Fatigue, etc |
Anouk E, etc. (2020) [40] | Three-arm RCT.HIIT + RT;HIIT + AT;UC | N = 240, stage I-IIIA BCS, mean age: RT: 52.2 ± 10.1 AT: 53.9 ± 7.4 | HIIT + RT; HIIT + AT, 16 wks, 2 d/wk,60 min | RT:79.5%; AT:82.1% | IL-6, TNF-α | Muscular strength, etc |