1st clinic (N = 1899) | 2nd clinic (N = 1968) | 3rd clinic (N = 1911) | |
---|---|---|---|
Age, mean (SD) | 50.5 (4.4) | 51.7 (4.4) | 52.8 (4.3) |
Years since FMP, mean (SD) | 1.9 (3.4) | 2.5 (3.8) | 3.2 (4.2) |
AMH (ng/ml), median (IQR) | 0.01 (0.01–0.17) | 0.01 (0.01–0.08) | 0.01 (0.01–0.03) |
FSH (mIU/ml), median (IQR) | 36.38 (7.56–74.88) | 57.97 (11.80–88.08) | 64.16 (19.04–89.14) |
LH (mIU/ml), median (IQR) | 24.55 (7.40–40.11) | 31.49 (10.56–44.58) | 31.86 (15.96–43.28) |
Menopausal stage | |||
Pre-menopause, % (N) | 38.6 (720) | 29.0 (523) | 21.7 (376) |
Peri-menopause, % (N) | 27.2 (507) | 28.3 (511) | 26.8 (465) |
Post-menopause, % (N) | 34.1 (636) | 42.7 (769) | 51.4 (891) |
Physical function | |||
Physical function composite score, mean (SD) | 1.34 (0.37) | 1.40 (0.37) | 1.39 ( 0.37) |
Grip strength (kg), mean (SD) | 26.04 (6.61) | 27.68 (6.09) | 28.03 ( 6.44) |
Inability to complete 30 s one-leg stand eyes open, % (N) | 15.9 (299) | 12.8 (249) | 18.9 (354) |
Inability to complete 3 s one-leg stand eyes closed, % (N) | 25.2 (473) | 31.3 (608) | 34.0 (636) |
Walking speed less than 1.1 m/s, % (N) | 25.2 (474) | 19.8 (388) | 17.2 (325) |
Inability to complete 10 chair rises in 26 s, % (N) | 26.0 (478) | 17.2 (329) | 15.3 (283) |
Education | |||
CSE/vocational/O-level, % (N) | 45.9 (871) | ||
A-level, % (N) | 30.4 (578) | ||
Degree, % (N) | 23.7 (450) | ||
Smoking status | |||
Never smoker, % (N) | 56.3 (1069) | ||
Former smoker, % (N) | 35.9 (682) | ||
Current smoker, % (N) | 7.8 (148) | ||
Age at first pregnancy, mean (SD) | 26.7 (4.7) | ||
BMI, mean (SD) | 26.2 (5.0) | 26.3 (5.2) | 26.2 (5.3) |