Skip to main content

Table 2 Overall survival rate of breast cancer patients who developed a second primary malignancy with different characteristics, n (%)

From: Predictive models for overall survival in breast cancer patients with a second primary malignancy: a real-world study in Shanghai, China

Variables

1-year

3-years

5-years

10-years

15-years

Survival

Death

p

Survival

Death

p

Survival

Death

p

Survival

Death

p

Survival

Death

p

Number

163 (100.00)

0

 

153 (89.57)

10 (6.13)

 

144 (88.34)

19 (11.66)

 

105 (64.42)

58 (35.58)

 

92 (56.44)

71 (43.56)

 

Age at BC diagnosis (years)

 

–

  

1.000

  

0.145

  

0.147

  

0.015

 

  < 56

102 (100.00)

0

 

96 (94.12)

6 (5.88)

 

93 (91.18)

9 (8.82)

 

70 (68.63)

32 (31.37)

 

65 (63.73)

37 (36.28)

 

  ≥ 56

61 (100.00)

0

 

57 (93.44)

4 (6.56)

 

51 (83.61)

10 (16.39)

 

35 (57.38)

26 (42.62)

 

27 (44.26)

34 (55.74)

 

Age at SPM diagnosis (years)

 

–

  

1.000

  

0.983

  

0.418

  

0.011

 

  < 62

94 (100.00)

0

 

88 (93.62)

6 (6.38)

 

83 (88.30)

11 (11.70)

 

63 (67.02)

31 (32.98)

 

61 (64.89)

33 (35.11)

 

  ≥ 62

69 (100.00)

0

 

65 (94.20)

4 (5.80)

 

61 (88.41)

8 (11.59)

 

42 (60.87)

27 (39.13)

 

31 (44.93)

38 (55.07)

 

TNM stage of BCa

  

–

  

0.229

  

0.975

  

0.810

  

0.252

  I + II

119 (100.00)

0

 

111 (93.28)

8 (6.72)

 

105 (88.24)

14 (11.76)

 

79 (66.39)

40 (33.61)

 

70 (58.82)

49 (41.18)

 

  III + IV

12 (100.00)

0

 

10 (83.33)

2 (16.67)

 

10 (83.33)

2 (16.67)

 

7 (58.33)

5 (41.67)

 

5 (41.67)

7 (58.33)

 

TNM stage of SPMa

  

–

  

1.000

  

0.135

  

 < 0.001

  

 < 0.001

  I + II

59 (100.00)

0

 

57 (96.61)

2 (3.39)

 

57 (96.61)

2 (3.39)

 

52 (88.14)

7 (11.86)

 

50 (84.74)

9 (15.25)

 

  III + IV

36 (100.00)

0

 

35 (97.22)

1 (2.78)

 

31 (86.11)

5 (13.89)

 

16 (44.44)

20 (55.56)

 

13 (36.11)

23 (63.89)

 

BC therapeutic hospital grade

 

–

  

0.838

  

0.537

  

0.302

  

0.103

 

  Tertiary

101 (100.00)

0

 

94 (93.07)

7 (6.93)

 

88 (87.13)

13 (12.87)

 

62 (61.39)

39 (38.61)

 

52 (51.49)

49 (48.51)

 

  Secondary

62 (100.00)

0

 

59 (95.16)

3 (4.84)

 

56 (90.32)

6 (9.68)

 

43 (69.35)

19 (30.65)

 

40 (64.52)

22 (35.48)

 

SPM therapeutic hospital grade

 

–

  

0.896

  

0.537

  

0.338

  

0.042

 

  Tertiary

125 (100.00)

0

 

118 (94.40)

7 (5.60)

 

112 (89.60)

13 (10.40)

 

83 (66.40)

42 (33.60)

 

76 (60.80)

49 (39.20)

 

  Secondary

38 (100.00)

0

 

35 (92.11)

3 (7.89)

 

32 (84.21)

6 (15.79)

 

22 (57.89)

16 (42.11)

 

16 (42.11)

22 (57.89)

 

Surgery for BCb

  

–

  

1.000

  

0.269

  

0.761

  

0.859

  Yes

80 (100.00)

0

 

83 (94.32)

5 (5.68)

 

80 (90.91)

8 (9.09)

 

49 (61.25)

31 (38.75)

 

46 (57.50)

34 (42.50)

 

  No

58 (100.00)

0

 

70 (93.33)

5 (6.67)

 

64 (85.33)

11 (14.67)

 

37 (63.79)

21 (36.21)

 

34 (58.62)

24 (41.38)

 

Surgery for SPM

  

–

  

0.102

  

0.192

  

 < 0.001

  

 < 0.001

  Yes

88 (100.00)

0

 

82 (93.18)

6 (6.82)

 

77 (87.50)

11 (12.50)

 

68 (77.27)

20 (22.73)

 

62 (70.45)

26 (29.55)

 

  No

75 (100.00)

0

 

64 (85.33)

11 (14.67)

 

60 (80.00)

15 (20.00)

 

37 (49.33)

38 (50.67)

 

30 (40.00)

45 (60.00)

 

SPM sitesc

               

  Colon and rectum

  

–

  

0.259

  

0.530

  

0.259

  

0.211

   Yes

30 (100.00)

0

 

30 (100.00)

0 (0)

 

28 (93.33)

2 (6.67)

 

22 (73.33)

8 (26.67)

 

20 (66.67)

10 (33.33)

 

   No

133 (100.00)

0

 

123 (92.48)

10 (7.52)

 

116 (87.22)

17 (12.78)

 

83 (62.41)

50 (37.59)

 

72 (54.14)

61 (45.86)

 

  Thyroid

  

–

  

0.292

  

0.254

  

 < 0.001

  

 < 0.001

   Yes

28 (100.00)

0

 

28 (100.00)

0

 

27 (96.43)

1 (3.57)

 

27 (96.43)

1 (3.57)

 

27 (96.43)

1 (3.57)

 

   No

135 (100.00)

0

 

125 (92.59)

10 (7.41)

 

117 (86.67)

18 (13.33)

 

78 (57.78)

57 (42.22)

 

65 (48.15)

70 (51.85)

 

  Lung and bronchus

 

–

  

0.344

  

0.628

  

0.832

  

0.491

 

   Yes

24 (100.00)

0

 

21 (87.50)

3 (12.50)

 

20 (83.33)

4 (16.67)

 

15 (62.50)

9 (37.50)

 

12 (50.00)

12 (50.00)

 

   No

139 (100.00)

0

 

132 (94.96)

7 (5.04)

 

124 (89.21)

15 (10.79)

 

90 (64.75)

49 (35.25)

 

80 (57.55)

59 (42.45)

 

Latency (years)

  

–

  

0.002

  

 < 0.001

  

0.647

  

0.017

  ≤ 5

77 (94.81)

0

 

67 (87.01)

10 (12.99)

 

58 (75.32)

19 (24.68)

 

51 (66.23)

26 (33.77)

 

51 (66.23)

26 (33.77)

 

  > 5

86 (100.00)

0

 

86 (100.00)

0 (0)

 

86 (100.00)

0 (0)

 

54 (62.79)

32 (37.21)

 

41 (47.67)

45 (52.33)

 
  1. Bold means statistic significance
  2. BC breast cancer, TNM tumour node metastasis, SPM second primary malignancy
  3. aPatients with an unclassified TNM stage were not included
  4. bPatients with an unknown status of surgery were not included
  5. cThe number of SPM sites in colon and rectum, thyroid and lung and bronchus ranked as the top three, were included
Back to article page

BMC Women's Health

ISSN: 1472-6874

Contact us