Table 1 A comparison to differentiate ACC from syringoma from clinical and gross histomorphological features
From: Adenoid Cystic Carcinoma (ACC) of the Bartholin's gland misdiagnosed for three times: a case report
Chondroid Syringoma | Adenoid Cystic Carcinoma | |
|---|---|---|
Clinical Manifestation | Painless, solid, ovoid or round mass | A painless lump with unspecific symptoms including local inflammation, pain, bleeding, pruritus and or dyspareunia with perineural infiltrations [4]. |
Histological features | Epithelial components include cuboidal, basaloid, squamous, spindle cell, plasmacytoid, and clear cells usually forming sheets or ducts Myoepithelial components contain spindle-shaped or plasmacytoid cells forming sheets, or appear as a reticular pattern Mesenchymal components are myxoid/mucoid, cartilaginous or hyalinised [6]. | Acellular spaces containing mucin and hyalinized material Uniform small cells forming cords and nests surrounding the acellular spaces The tumor cells are basaloid, with little cytoplasm and regular nuclear structure [4]. |