Table 2 Metabolites concentrations increased from T1 to T4
Metabolite name | Metabolite | Mean baseline | Mean time 4 | Baseline vs. Time 4 p value | Time4 Baseline (FC) | Log p Value | m/z | RT |
|---|---|---|---|---|---|---|---|---|
Diallylamine | 4078 98.0964 7.99 NA P | 11583397.44 | 34950234.03 | 3.74E-14 | 3.02 | 13.43 | 98.0964 | 7.99 |
N,N,N-Trimethylethenaminium | 41,408 86.0966 7.7 NA P | 6800588.49 | 19335002.09 | 5.62E-14 | 2.84 | 13.25 | 86.0966 | 7.7 |
2-Imino-4-methylpiperidine | 4634 113.1071 6.92 NA P | 3687620.29 | 8959504.60 | 6.22E-14 | 2.43 | 13.21 | 113.107 | 6.92 |
3-hydroxyheptanoylcarnitine | 5479 272.1859 1.53 NA P | 449425.96 | 1402870.68 | 6.32E-14 | 3.12 | 13.20 | 272.186 | 1.53 |
Piperidine | 34,329 86.0966 7.46 NA P | 21866796.91 | 56688809.2 | 1.36E-13 | 2.59 | 12.87 | 86.0966 | 7.46 |
10-(beta-Dimethylaminopropionyl) phenothiazine | 2354 297.1096 2.3 NA N | 151118.01 | 308877.67 | 1.39E-12 | 2.04 | 11.86 | 297.11 | 2.3 |
Melatonin | 4177 215.118 1.45 NA P | 1536816.2 | 4636613.02 | 5.92E-11 | 3.02 | 10.23 | 215.118 | 1.45 |
Dibutyl sulfosuccinate | 2170 309.1 4.1 NA N | 100243.05 | 400677.00 | 9.32E-11 | 4.00 | 10.03 | 309.1 | 4.1 |
N-heptanoyl-homoserine lactone | 3069 214.1436 1.77 NA P | 130167.86 | 272694.11 | 4.54E-09 | 2.09 | 8.34 | 214.144 | 1.77 |
2-Acetylpyrrolidine | 3642 114.0917 1.53 NA P | 5846166.59 | 12053728.14 | 8.39E-09 | 2.06 | 8.08 | 114.092 | 1.53 |
Dibutyl sulfosuccinate | 8892 309.1 4.22 NA N | 114923.23 | 382686.68 | 5.01E-08 | 3.33 | 7.30 | 309.1 | 4.22 |
Gluconolactone | 1898 177.0388 1.83 NA N | 2818207.46 | 6947468.86 | 2.29E-07 | 2.47 | 6.64 | 177.039 | 1.83 |
3-Indoleacetonitrile | 4957 157.0761 1.45 NA P | 324709.14 | 744430.84 | 1.39E-06 | 2.29 | 5.86 | 157.076 | 1.45 |
Pentanamide | 41,401 102.0912 1.97 NA P | 53199585.96 | 153718573.2 | 1.96E-06 | 2.89 | 5.71 | 102.091 | 1.97 |
PYRROLIDINE-2-CARBALDEHYDE | 10,219 100.0756 1.99 NA P | 784390.43 | 2159792.49 | 2.77E-06 | 2.75 | 5.56 | 100.076 | 1.99 |
Erucin | 9482 160.0268 7.09 NA N | 212884.86 | 433015.68 | 2.77E-06 | 2.03 | 5.56 | 160.027 | 7.09 |
2-Dehydro-D-xylonate | 9374 163.0232 1.79 NA N | 3557348.17 | 9730937.79 | 5.43E-06 | 2.74 | 5.27 | 163.023 | 1.79 |
L,L-Cyclo(leucylprolyl) | 2796 211.1441 1.54 NA P | 964539.33 | 2463282.94 | 1.45E-05 | 2.55 | 4.84 | 211.144 | 1.54 |
Acetoxy-6-gingerol | 11,599 337.2015 1.35 NA P | 91213.95 | 204863.25 | 3.71E-05 | 2.25 | 4.43 | 337.202 | 1.35 |
4-Pyridoxolactone | 17,622 164.0359 2.76 NA N | 1603488.18 | 4054200.12 | 5.04E-05 | 2.53 | 4.30 | 164.036 | 2.76 |
3-Deaza-2’-deoxyadenosine | 15,641 249.0972 1.89 NA N | 118347.38 | 244849.99 | 0.00016379 | 2.07 | 3.79 | 249.097 | 1.89 |
1-hydroxyquinoline | 26,405 146.0604 1.9 NA P | 153524.47 | 439734.84 | 0.000497011 | 2.86 | 3.30 | 146.06 | 1.9 |
2,5-dihydro-2,4-dimethyloxzaxole | 40,029 100.0758 3.4 NA P | 245702.28 | 2407164.498 | 0.001091549 | 9.80 | 2.96 | 100.076 | 3.4 |
(R)-3-Hydroxy-5-phenylpentanoic acid | 649 193.0886 1.72 NA N | 2706828.94 | 5587170.165 | 0.001804092 | 2.06 | 2.74 | 193.089 | 1.72 |
Asparaginyl-Aspartate | 15,831 246.0735 3.53 NA N | 523376.61 | 1144979.991 | 0.007315639 | 2.19 | 2.14 | 246.074 | 3.53 |
4-Pyridoxic acid | 8339 164.0333 1.76 NA N | 270610.22 | 866546.7403 | 0.020716043 | 3.20 | 1.68 | 164.033 | 1.76 |
2-Hydroxy-3-morpholinopropanesulfonic Acid | 10,291 224.0598 3.48 NA N | 228396.41 | 649190.9916 | 0.036567075 | 2.84 | 1.44 | 224.06 | 3.48 |
N-Dimethyl-2-aminoethylphosphonate | 1850 154.0633 3.13 NA P | 246486.34 | 593936.6879 | 0.07293061 | 2.41 | 1.14 | 154.063 | 3.13 |