Fig. 1

A An image of slides showing the hematoxyline eosin (HE)-stained and immunohistochemical analysis of angiotensin converting enzyme 2 (ACE2)- and trans-membrane serine protease 2 (TMPRSS2)-stained cells in the pre-pandemic (upper row) and in-pandemic endometria (lower row) with corresponding positive controls (testis for ACE2 and kidney for TMPRSS2) and negative controls. B and C Shows the immunoreactivity of ACE2 and TMPRSS2 as measured by the immunoreactive score (IRS) in pre-pandemic and in-pandemic endometria. The procedure of IRS measurement is described in methods. Mann–Whitney U test indicated no significance difference in the expression of ACE2 and TMPRSS2 between these two groups of endometria. The boxes represent the interquartile ranges and horizontal lines in the boxes represent median values. Scale bar = 50 μm for each slide