Table 4 Associations of female reproductive tract infections and estrogen exposure with breast cancer prognosis

Reproductive tract infections

 No

3579

262 (7.3)

1.00 (reference)

1.00 (reference)

494 (13.8)

1.00 (reference)

1.00 (reference)

 Yes

685

37 (5.4)

0.59 (0.42,0.83)

0.61 (0.40,0.94)

104 (15.1)

0.85 (0.68,1.05)

0.84 (0.65,1.09)

Number of menstrual cycles

  ≤ 327

1105

86 (7.8)

1.00 (reference)

1.00 (reference)

177 (16.0)

1.00 (reference)

1.00 (reference)

  > 327

2208

164 (7.4)

0.96 (0.74,1.24)

0.82 (0.57, 1,18)

304 (13.8)

0.87 (0.72,1.05)

0.92 (0.70,1.21)

Reproductive time—Duration of parity—Breastfeeding duration (years)

  ≤ 25

1147

88 (7.7)

1.00 (reference)

1.00 (reference)

184 (16.0)

1.00 (reference)

1.00 (reference)

  > 25

2307

170 (7.4)

0.98 (0.76,1.27)

0.78 (0.51,1.17)

318 (13.8)

0.88 (0.74,1.06)

1.02 (0.73,1.42)

Reproductive time—Duration of all pregnancies—Breastfeeding duration (years)

  ≤ 25

1100

88 (8.0)

1.00 (reference)

1.00 (reference)

179 (16.3)

1.00 (reference)

1.00 (reference)

  > 25

2195

163 (7.4)

0.94 (0.73,1.23)

0.70 (0.47,1.06)

309 (14.1)

0.89 (0.74,1.07)

1.01 (0.72,1.41)