Table 3 Overview of the guidelines for unexplained infertility in the United Stated, the United Kingdom and the Netherlands
Guideline | Tubal patency test | Treatment | |
|---|---|---|---|
Low risk for tubal pathology | High risk for tubal pathology | ||
ASRM, the United States (5) | HSG | HSG | 3–4 Cycles of hormonal stimulated IUI before starting IVF |
NICE, the United Kingdom (4) | HSG | Laparoscopy | In total 2 years of regular unprotected intercourse before starting IVF |
NVOG, the Netherlands (6) | No tubal patency test | HSG | Favorable chance to conceive (> 30%, based on the Hunault prediction score(14)) within 1 year: 6–12 months expected management, before start of 6 cycles hormonal stimulated IUI followed by IVF. Unfavorable chance (< 30%): 6 hormonally stimulated IUI cycles followed by IVF |