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Table 3 Determinants of hyperemesis gravidarum among pregnant women who visit antenatal care at public & private hospitals in Bahir Dar city, North-West Ethiopia, 2022 (N = 444)

From: Determinants of hyperemesis gravidarum among pregnant women attending antenatal care at public and private hospitals in Bahir Dar City, North-West Ethiopia, 2022: a multicenter unmatched case control study

Characteristics

Category

Case N (%)

Control N (%)

COR(95% CI)

AOR(95% CI)

P-value

Residency

Urban

111(75)

155(52.4)

2.729(1.764,4.222)

2.717(1.639,4.502)**

< 0.001

Rural

37(25)

141(47.6)

1

1

 

Oslo social support scale(OSSS-3)

Poor social support

24(16.2)

23(7.8)

1.913(1.003,3.649)

2.008(0.935,4.312)

0.074

Moderate social support

58(39.2)

152(51.4)

0.700(0.457,1.071)

0.754(0.453,1.254)

0.276

Strong social support

66(44.6)

121(40.8)

1

1

 

Gravidity

Primigravida

39(26.4)

19(6.4)

5.216(2.887,9.424)

6.185(3.135,12.202)**

< 0.001

Multigravida

109(73.6)

277(93.6)

1

1

 

Types of gestation

Singleton

141(95.3)

289(97.6 )

1

1

 

Multiple

7(4.7)

7(2.4)

2.050(0.705,5.958)

1.576(0.452,5.496)

0.475

GA in weeks

1st trimester

96(64.9)

121(40.9)

8.727(3.030,25.141)

9.301(2.877,30.067)**

< 0.001

2nd trimester

48(32.4)

134(44.3)

4.0331(1.375,11.817)

4.785(1.449,15.805)*

0.010

3rd trimester

4(2.7)

84(14.9)

1

1

 

Family history of HEG

Yes

38(25.7)

20(6.8)

1.411(0.835,2.386)

5.020(2.599,9.697)**

< 0.001

No

110(74.3)

276(93.2)

1

1

 

History of pre-pregnancy motion sickness

Yes

28(18.9)

42(14.2)

2.387(1.418,4.018)

1.706(0.893,3.262)

0.106

No

120(81.1)

254(85.8)

1

1

 

Helicobacter Pylori serostatus

Positive

28(18.9)

17(5.7)

3.829(2.020,7.259)

4.369(2.014,9.480)**

< 0.001

Negative

120(81.1)

279(94.3)

1

1

 

Depression

Yes

21(14.2)

21(7.1)

2.165(1.141,4.108)

2.195(1.004,4.797)*

0.049

No

127(85.8)

275(92.9)

1

1

  1. * = p-value < 0.05; ** = p-value < 0.001; 1 = Reference; AOR = Adjusted Odd Ratio, COR = crude odds ratio, CI = Confidence interval