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Fig. 4 | BMC Women's Health

Fig. 4

From: Differential molecular pathway expression according to chemotherapeutic response in ovarian clear cell carcinoma

Fig. 4

Postulated mechanisms involved in platinum-resistant OCCC. Red box/circle: significantly upregulated gene; blue box, significantly downregulated gene; gray box/circle: not significantly expressed gene or not included in this panel. GF, growth factor; FGF, fibroblast growth factor; NGF, nerve growth factor; EFNA5, ephrin-A5; ECM, extracellular matrix; RELN, reelin; RTK, receptor tyrosine kinase; PDGFRA, platelet-derived growth factor receptor, alpha polypeptide; ITGB8, integrin, beta 8; ITGA8, integrin, alpha 8; GRB2, growth factor receptor-bound protein-2; GSK3, glycogen synthase kinase-3; CCND1, cyclin D1; CCDN3, cyclin D3

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