| All-cause mortality | CVD mortality |
---|
Unadjusted Model | Adjusted Model | Unadjusted Model | Adjusted Model |
---|
Variables | HR (95%CI) | P | HR (95%CI) | P | HR (95%CI) | P | HR (95%CI) | P |
---|
NLR | 1.24 (1.14–1.34) |  < 0.001 | 1.17 (1.09–1.26) |  < 0.001 | 1.21 (1.11–1.33) |  < 0.001 | 1.16 (1.04–1.29) | 0.007 |
PLR | 1.06 (0.97–1.16) | 0.224 | 1.05 (0.98–1.13) | 0.131 | 1.00 (0.86–1.16) | 0.972 | 0.98 (0.88–1.09) | 0.669 |
MLR | 1.36 (1.29–1.43) |  < 0.001 | 1.16 (1.08–1.25) |  < 0.001 | 1.41 (1.31–1.52) |  < 0.001 | 1.18 (1.05–1.33) | 0.005 |
SII | 1.18 (1.10–1.26) |  < 0.001 | 1.11 (1.04–1.18) |  < 0.001 | 1.12 (1.00–1.26) | 0.043 | 1.09 (0.97–1.23) | 0.156 |
SIRI | 1.36 (1.29–1.44) |  < 0.001 | 1.21 (1.12–1.30) |  < 0.001 | 1.37 (1.25–1.51) |  < 0.001 | 1.27 (1.10–1.46) |  < 0.001 |
AISI | 1.26 (1.18–1.34) |  < 0.001 | 1.13 (1.06–1.20) |  < 0.001 | 1.24 (1.10–1.39) |  < 0.001 | 1.15 (1.01–1.30) | 0.032 |
- AISI, neutrophil × monocyte × platelet /lymphocyte ratio, CI Confidence interval, CVD Cardiovascular disease, HR Hazard ratio, MLR Monocyte-to-lymphocyte ratio, NLR Neutrophil-to-lymphocyte ratio, PLR Platelet-to-lymphocyte ratio, SII Immune-inflammation index, SIRI Systemic inflammation response index
- For the all-cause mortality, age, race, education, marital status, the severity of osteoporosis, poverty-to-income ratio (PIR), smoking status, total cholesterol, glucose, systolic blood pressure (SBP), diastolic blood pressure (DBP), body mass index (BMI), central obesity, history of CVD, history of fracture, diabetes, lipid-lowering drugs, osteoporosis drugs, occupation, and energy intake were adjusted for; adjusted covariates for the CVD mortality included age, race, education, marital status, the severity of osteoporosis, PIR, high density lipoprotein cholesterol (HDL-C), total cholesterol, glucose, SBP, DBP, BMI, central obesity, CVD history, fracture history, diabetes, lipid-lowering drugs, and occupation