The increased risk of colorectal cancer in the women who underwent hysterectomy from the South Korean National Health Insurance Database

Table 4 Hazard ratios of all-cause mortality in participants with Gastrointestinal cancer from the Korea National Health Insurance Database, 2007–2020

	Adjusted^a
	HR (95% CI)^a	p-value^*
Colon cancer
Reference (no hysterectomy)	1 (reference)
Hysterectomy alone	2.405 (0.385–15.018)	0.348
Hysterectomy + adnexal surgery	1 (0-Infinite)	0.993
Colorectal cancer
Reference (no hysterectomy)	1 (reference)
Hysterectomy alone	3.369 (0.641–17.719)	0.152
Hysterectomy + adnexal surgery	1 (0-Infinite)	0.991
Gastrointestinal cancer
Reference (no hysterectomy)	1 (reference)
Hysterectomy alone	3.495 (1.347–9.07)	0.001
Hysterectomy + adnexal surgery	1.913 (0.535–6.844)	0.319

CCI Charlson comorbidity index, CI confidence interval, HR hazard ratio, MHT menopausal hormone therapy, SES socioeconomic status
^*p-value less than 0.05 is statistically significant
^aHRs were adjusted for hysterectomy, age, SES, regrion, CCI, parity, menopause before inclusion, MHT before inclusion, adnexal surgery before inclusion, diseases of the gallbladder and biliary tract before inclusion, uterine leiomyoma, endometriosis

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