Interaction of estradiol and vitamin D with low skeletal muscle mass among middle-aged and elderly women

BMC Women's Health

Table 4 Odds ratios for the combined association of estradiol quartiles and vitamin D deficiency status with low SMM.

Estradiol and Vitamin D deficiency	Unadjusted Model		Model 1		Model 2		Model 3
Estradiol and Vitamin D deficiency	OR (95%CI)	P value	OR (95%CI)	P value	OR (95%CI)	P value	OR (95%CI)	P value
Q1 + VD deficiency	3.849 (1.393, 10.634)	0.009	2.776 (0.985,7.824)	0.053	2.879 (1.021,8.123)	0.046	3.898 (1.155,13.160)	0.028
Q2 + VD deficiency	3.921 (1.391, 11.059)	0.010	2.946 (1.021,8.502)	0.046	3.047 (1.054,8.802)	0.040	4.801 (1.378,16.721)	0.014
Q3 + VD deficiency	2.987 (1.068, 8.355)	0.037	2.628 (0.924,7.479)	0.070	2.738 (0.961,7.8025)	0.059	4.709 (1.365,16.251)	0.014
Q4 + VD deficiency	0.768 (0.255, 2.313)	0.639	0.910 (0.295,2.807)	0.870	0.941 (0.304,2.910)	0.916	1.970 (0.527,7.365)	0.314
Q1 + non-VD deficiency	3.057 (0.887, 10.538)	0.077	2.389 (0.679,8.405)	0.175	2.530(0.717,8.921)	0.149	3.416 (0.766,15.237)	0.107
Q2 + non-VD deficiency	4.338 (1.160, 16.226)	0.029	3.437 (0.898,13.148)	0.071	3.637 (0.948,13.955)	0.060	3.948 (0.745,20.935)	0.107
Q3 + non-VD deficiency	2.548 (0.692, 9.375)	0.159	2.368 (0.631,8.891)	0.201	2.488 (0.650,9.217)	0.186	4.454 (0.914,21.711)	0.065
Q4 + non-VD deficiency	Reference		Reference		Reference		Reference

Notes: Bold indicates statistical significance. The model 1 adjusted for age, residence, marital status, educational level, BMI and fat mass; Model 2 adjusted for model 1 and smoking status, drinking status, physical activity; Model 3 adjusted for model 2 and triglyceride, menopausal status, dietary energy

ISSN: 1472-6874