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Table 5 Odds ratios for the combined association of estradiol quartiles and vitamin D quartiles with low SMM.

From: Interaction of estradiol and vitamin D with low skeletal muscle mass among middle-aged and elderly women

Vitamin D and Estradiol

Unadjusted Model

 

Model 1

 

Model 2

 

Model 3

OR (95%CI)

P value

 

OR (95%CI)

P value

 

OR (95%CI)

P value

 

OR (95%CI)

P value

VD Q1 + estradiol Q1

3.339 (1.506,7.404)

0.003

 

2.140 (0.920,4.982)

0.077

 

2.178 (0.936,5.073)

0.071

 

2.466 (0.906,6.711)

0.077

VD Q1 + estradiol Q2

7.008 (3.061,6.048)

< 0.001

 

4.915 (2.035,11.871)

< 0.001

 

4.964 (2.054,11.996)

< 0.001

 

5.849 (2.012,17.004)

0.001

VD Q1 + estradiol Q3

4.818 (2.128,10.907)

< 0.001

 

3.651 (1.545,8.629)

0.003

 

3.704 (1.566,8.758)

0.003

 

5.068 (1.783,14.403)

0.002

VD Q1 + estradiol Q4

0.723 (0.232,2.249)

0.575

 

0.756 (0.239,2.391)

0.634

 

0.751 (0.237,2.377)

0.626

 

1.031 (0.280,3.791)

0.964

VD Q2 + estradiol Q1

5.154 (2.387,11.130)

< 0.001

 

3.35 (1.485,7.556)

0.004

 

3.393 (1.503,7.659)

0.003

 

3.409 (1.290,9.006)

0.013

VD Q2 + estradiol Q2

4.452 (1.841,0.767)

0.001

 

2.731 (1.078,6.918)

0.034

 

2.742 (1.081,6.955)

0.034

 

3.045 (0.911,9.359)

0.052

VD Q2 + estradiol Q3

2.058 (0.844,5.020)

0.113

 

1.466 (0.579,3.712)

0.419

 

1.493 (0.59,3.781)

0.398

 

1.795 (0.600,5.369)

0.295

VD Q2 + estradiol Q4

0.655 (0.194,2.214)

0.496

 

0.707 (0.208,2.410)

0.580

 

0.715 (0.210,2.441)

0.593

 

1.093 (0.278,4.298)

0.899

VD Q3 + estradiol Q1

2.703 (1.170,6.244)

0.020

 

1.856 (0.772,4.458)

0.167

 

1.879 (0.782,4.518)

0.159

 

1.731 (0.611,4.902)

0.302

VD Q3 + estradiol Q2

1.711 (0.626,4.675)

0.295

 

1.216 (0.429,3.449)

0.714

 

1.243 (0.438,3.527)

0.683

 

1.764 (0.536,5.804)

0.350

VD Q3 + estradiol Q3

3.012 (1.310,6.927)

0.009

 

2.59 (1.096,6.121)

0.030

 

2.662 (1.125,6.298)

0.026

 

4.117 (1.420,11.934)

0.009

VD Q3 + estradiol Q4

0.681 (0.219,2.118)

0.507

 

0.713 (0.227,2.237)

0.563

 

0.731 (0.232,2.297)

0.591

 

1.101 (0.295,4.135)

0.882

VD Q4 + estradiol Q1

3.219 (1.424,7.275)

0.005

 

2.183 (0.926,5.147)

0.074

 

2.256 (0.956,5.324)

0.063

 

2.288 (0.295,4.135)

0.109

VD Q4 + estradiol Q2

2.849 (1.130,7.178)

0.026

 

2.144 (0.818,5.615)

0.121

 

2.191 (0.835,5.751)

0.111

 

2.062 (0.643,6.620)

0.224

VD Q4 + estradiol Q3

1.816 (0.726,4.544)

0.202

 

1.685 (0.654,4.339)

0.280

 

1.721 (0.668,4.436)

0.261

 

1.958 (0.626,6.122)

0.248

VD Q4 + estradiol Q4

Reference

  

Reference

  

Reference

  

Reference

 
  1. Notes: Bold indicates statistical significance. The model 1 adjusted for age, residence, marital status, educational level, BMI and fat mass; Model 2 adjusted for model 1 and smoking status, drinking status, physical activity; Model 3 adjusted for model 2 and triglyceride, menopausal status, dietary energy
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