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Table 7 Multiple analysis of side effects, type of medication used, and treatment interruption

From: Tolerability of endometriosis medical treatment: a comparison between combined hormonal contraceptives and progestins

Treatment Type and Side Effect

"p" Value of Univariate Analysis

Univariate Analysis OR (CI)

"p" Value of Adjusted Analysis

Adjusted Analysis OR (CI)

Spotting

 < 0.001

2.267 (1.457–3.528)

 < 0.001

2.672 (1.672–4.269)

EP

0.016

1.725 (1.106–2.692)

0.005

1.995 (1.237–3.219)

Persistence of Pain

0.043

1.619 (1.015–2.582)

0.043

1.670 (1.017–2.743)

Weight Gain

0.066

2.330 (0.946–5.740)

0.017

3.227 (1.237–8.418)

Headache

0.080

3.994 (0.849–18.778)

0.076

4.440 (0.855–23.060)

  1. OR Odds Ratio, CI confidence interval, EP combined contraceptives containing estrogens and progestins