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Table 8 Multivariate analysis of the correlation between side effects, education, staging, and follow-up time with the risk of interrupting EP treatment

From: Tolerability of endometriosis medical treatment: a comparison between combined hormonal contraceptives and progestins

Side Effect

"p" Value of Univariate Analysis

Univariate Analysis OR (CI)

"p" Value of Adjusted Analysis

Adjusted Analysis OR (CI)

Spotting

 < 0.001

4.267 (2.028–8.978)

 < 0.001

8.432 (2.632–27.014)

Persistence of Pain

0.117

1.769 (0.898–3.610)

0.006

6.388 (1.721–23.714)

Infertility

0.136

0.533 (0.234–1.218)

0.010

0.153 (0.037–0.632)

Duration of Treatment Less than 9 Months

0.041

3.291 (1.048–10.335)

0.067

4.550 (0.8990–23.009)

Staging Minimal/Mild

0.155

2.106 (0.755–5.874)

0.026

5.578 (1.233–25.233)

University Degree

0.236

0.636 (0.331–1.344)

0.429

0.619 (0.188–2.032)

Headache

0.299

2.348 (0.469–11.742)

0.435

2.741 (0.217–34.491)

  1. EP combined contraceptives containing estrogens and progestins, OR Odds Ratio, CI confidence interval