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Table 9 Multivariate analysis of the correlation between side effects, stage, and parity with the risk of treatment interruption with P

From: Tolerability of endometriosis medical treatment: a comparison between combined hormonal contraceptives and progestins

Side Effect

"p" Value of Univariate Analysis

Univariate Analysis OR (CI)

"p" Value of Adjusted Analysis

Adjusted Analysis OR (CI)

Duration of Treatment Less than 9 Months

 < 0.001

5.625 (2.410–13.130)

 < 0.001

9.398 (3.006–29.378)

Spotting

0.057

1.775 (0.984–3.203)

0.024

2.638 (1.134–6.136)

Weight Gain

0.073

2.405 (0.923–6.271)

0.211

2.110 (0.655–6.796)

Intense Bleeding

0.086

4.062 (0.821–20.104)

0.308

3.443 (0.319–37.174)

Staging Minimal/Mild

0.005

5.206 (1.654–16.382)

0.001

8.078 (2.291–28.482)

Nulliparity

0.171

1.538 (0.830–2.852)

0.239

1.667 (0.711–3.907)

  1. P progestins, OR Odds Ratio, IC confidence interval