FOXO3 and PTEN expression in the ovary of girls with extra-gonadal cancer with or without chemotherapy treatment prior to cryopreservation

Table 2 Counting of PTEN-positive and PTEN-negative primordial follicles in patients that received (Group 1) and not received (Group 2) chemotherapy and/or radiotherapy before surgery for cryopreservation

	Patient	Age (years)	Total Follicle count	Primordial follicle
		Age (years)		PTEN⁻	PTEN⁺
Group 1	4	9	58	51	7
	5	10	29	29	0
	10	12	70	70	0
	11	13	31	30	1
	13	13	74	72	2
	23	16	23	22	1
	26	18	9	9	0
	27	19	10	10	0
	Total Count		304	293	11
	Total Count (%)		100,00	96,38	3,62^#
Group 2	1	7	25	24	1
	2	9	40	40	0
	3	9	33	11	22
	6	10	21	21	0
	7	11	104	59	45
	8	12	41	41	0
	9	12	8	8	0
	12	13	13	13	0
	14	14	31	31	0
	15	14	61	58	3
	16	14	272	253	19
	17	14	30	18	12
	18	14	15	15	0
	19	15	48	46	2
	20	15	179	177	2
	21	15	49	47	2
	22	15	167	167	0
	24	18	35	12	23
	25	18	10	9	1
	Total Count		1.182	1.050	132
	Total Count (%)		100,00	88,83	11,17^#

^#Percentage PTEN⁺ values for groups 1 and 2 exhibited statistically significant differences; Tukey test, α:0.05; p < 0.0001

ISSN: 1472-6874