Impact of nausea/vomiting on EQ-5D-5L utility scores in patients taking iron preparations for heavy menstrual bleeding or anemia

Table 2 Results of Multivariate analysis

EQ-5D-5L utility score	Coefficient	SE	t	P > t	95% Confidence Interval
Symptom_nausea/vomiting	-0.12198	0.01639	-7.44	0	-0.15421	-0.08975
Symptom_anemia	-0.09218	0.018764	-4.91	0	-0.12908	-0.05529
Symptom_menstrual pain	-0.08576	0.017225	-4.98	0	-0.11962	-0.05189
Symptom_PMS	-0.05925	0.017211	-3.44	0.001	-0.09309	-0.02541
Primary disease_PMS	-0.04641	0.019581	-2.37	0.018	-0.08491	-0.00791
Constant term	0.945575	0.016834	56.17	0	0.912476	0.978675

When the explanatory variable increases by 1, the EQ-5D-5L utility score can be interpreted as increasing by that coefficient
For example, if all the other conditions are the same, but the presence or absence of nausea/vomiting is different, it can be interpreted as 0.12198 lower for those with nausea/vomiting compared to those without nausea/vomiting
EQ-5D-5L, 5-level EQ-5D version; PMS, premenstrual syndrome; SE, standard error

a) Linear Model (LM)

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