Table 2 Current early pregnancy failure characteristics and treatment outcomes
Parameter | No retained placenta (n = 237) | Retained placenta (n = 34) | P value |
|---|---|---|---|
Method of conception | 0.086 | ||
Spontaneous | 208/235 (88.5) | 31/33 (93.9) | |
IUI | 5/235 (2.1) | 2/33 (6.1) | |
IVF | 22/235(9.4) | 0 (0) | |
Week of gestation | 9.4 ± 2.0 | 9.4 ± 1.7 | 0.99 |
Week of gestation by US | 6.8 ± 1.3 | 6.8 ± 1.2 | 0.98 |
Diagnosis | 0.90 | ||
Missed abortion | 204 (86.1) | 29 (85.3) | |
Blighted ovum | 33 (13.9) | 5 (14.7) | |
Presence of gestational sac | 229/232 (98.7) | 32/32 (100) | 0.52 |
Presence of yolk sac | 102/208 (49.0) | 21/32 (65.6) | 0.081 |
Presence of embryo | 160/230 (69.6) | 24/32 (75.0) | 0.53 |
Presence of embryonic pulse prior to diagnosis of EPF | 26/232 (11.2) | 0 (0) | 0.046 |
Gestational sac size z axis-mm | 20.8 ± 12.1 | 22 ± 15.2 | 0.81 |
Gestational sac size width-mm | 23.5 ± 13.6 | 27.2 ± 15.4 | 0.36 |
Gestational sac size length-mm | 32.5 ± 18.5 | 24.9 ± 15.6 | 0.037 |
Embryo size according to CRL | 8.9 ± 0.7 | 10.3 ± 1.7 | 0.47 |
Uterine size (weeks) | 7.2 ± 0.11 | 7.3 ± 0.40 | 0.83 |
Bleeding at diagnosis | 74 (31.2) | 8/33 (24.2) | 0.41 |
Misoprostol treatment success | 186 (78.5) | 21 (61.8) | 0.032 |
Of patients with success- number of doses of misoprostol | 0.035 | ||
One | 138/186 (74.2) | 11/21 (52.4) | |
Two | 48/186 (25.8) | 10/21 (47.6) |