Table 1 Distribution of pregnancy-associated cancer (PAC) and cancer-free women and the rate of PAC in strata of outcome of pregnancy according to maternal age and calendar year. Lombardy Region, 2010–2020

Maternal age

    < 30

98 (10.6)

163,677 (22.9)

0.60 (0.50–0.70)

38 (11.1)

66,540 (29.7)

0.57 (0.42–0.78)

    30–34

281 (30.4)

250,098 (34.9)

1.12 (1.10–1.26)

56 (16.4)

51,695 (23.1)

1.08 (0.83–1.40)

    35–40

425 (45.9)

250,557 (35.0)

1.69 (1.54–1.86)

148 (43.4)

73,447 (32.8)

2.01 (1.71–2.36)

    > 40

122 (13.2)

51,848 (7.2)

2.35 (1.97–2.80)

99 (29.0)

32,266 (14.4)

3.06 (2.51–3.72)

Calendar year at pregnancy

    2010

97 (10.5)

68,400 (9.6)

1.42 (1.16–1.73)

39 (11.4)

24,565 (11.1)

1.59 (1.16–2.17)

    2011

99 (10.7)

72,050 (10.1)

1.37 (1.13–1.67)

34 (10.0)

24,331 (10.9)

1.40 (1.00–1.95)

    2012

80 (8.6)

71,350 (10.0)

1.12 (0.90–1.39)

35 (10.3)

23,741 (10.6)

1.47 (1.06–2.05)

    2013

78 (8.4)

69,039 (9.6)

1.13 (0.90–1.41)

34 (10.0)

23,269 (10.4)

1.46 (1.04–2.04)

    2014

88 (9.5)

68,646 (9.6)

1.28 (1.04–1.58)

36 (10.6)

22,527 (10.1)

1.60 (1.15–2.21)

    2015

82 (8.9)

67,153 (9.4)

1.22 (0.98–1.51)

38 (11.1)

20,810 (9.3)

1.82 (1.33–2.50)

    2016

81 (8.8)

65,184 (9.10)

1.24 (1.00–1.54)

34 (10.0)

19,754 (8.8)

1.72 (1.23–2.40)

    2017

82 (8.9)

62,975 (8.8)

1.30 (1.05–1.61)

31 (9.1)

18,347 (8.2)

1.69 (1.19–2.39)

    2018

80 (8.6)

60,172 (8.4)

1.33 (1.07–1.65)

24 (7.0)

16,973 (7.6)

1.41 (0.95–2.10)

    2019

85 (9.2)

57,541 (8.0)

1.48 (1.19–1.82)

16 (4.7)

15,880 (7.1)

1.01 (0.62–1.63)

    2020

74 (8.0)

53,670 (7.5)

1.38 (1.10–1.73)

20 (5.9)

13,751 (6.1)

1.45 (0.94–2.24)