Table 1 General characteristics of included studies
Author | Year | Country | Design | Ethnicity | Endometriosis | Healthy control | Other benign tumors | Type | Stage | Cut off point | SN | SP | NOS score | |||||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
Stage I/II | Stage III/ IV | |||||||||||||||||||||
N | NLR | N | NLR | N | NLR | Type of endometrioma | N | NLR | N | NLR | N | NLR | ||||||||||
Cho | 2008 | South Korea | Retrospective | East Asian | 231 | 2.66 ± 0.34 | 384 | 1.99 ± 0.14 | 145 | 2.31 ± 0.32 | _ | _ | _ | _ | _ | _ | _ | _ | 2.01 | 60 | 60 | 7 |
Hua | 2013 | China | Retrospective | East Asian | 197 | 2.30 ± 0.25 | 112 | 1.68 ± 0.14 | 102 | 1.93 ± 0.19 | _ | _ | _ | _ | _ | _ | _ | _ | 1.82 | 58 | 65 | 7 |
Sayan | 2013 | Turkey | Prospective | Caucasian | 50 | 5.28 ± 2.28 | 50 | 5.06 ± 2.87 | _ | _ | _ | _ | _ | _ | 18 | 3.41 ± 1.38 | 32 | 5.60 ± 2.47 | 2.19 | 76 | 82 | 6 |
Yavuzcan | 2013 | Turkey | Retrospective | Caucasian | 61 | 2.45 ± 1.73 | 33 | 2.11 ± 0.86 | _ | _ | Endometrioma | Yes | 33 | 2.40 ± 2.04 | _ | _ | _ | _ | _ | _ | _ | 6 |
No | 28 | 2.51 ± 1.37 | ||||||||||||||||||||
Tokmak | 2015 | Turkey | Retrospective | Caucasian | 467 | 2.80 ± 2.00 | 340 | 1.70 ± 0.50 | _ | _ | _ | _ | _ | _ | _ | _ | _ | _ | 1.9 | 70 | 74 | 8 |
Li | 2016 | China | Prospective | East Asian | 100 | 2.43 ± 0.29 | 100 | 1.48 ± 0.52 | 60 | 1.64 ± 0.65 | _ | _ | _ | _ | _ | _ | _ | _ | _ | _ | _ | 8 |
Vigano | 2017 | Italy | Retrospective | Caucasian | _ | _ | _ | _ | _ | _ | Deep lesions | Yes | 69 | 2.17 ± 1.68 | 45 | 2.43 ± 2.19 | 124 | 2.08 ± 0.95 | _ | _ | _ | 6 |
No | 145 | 2.16 ± 1.25 | ||||||||||||||||||||
Peritoneal lesions | Yes | 58 | 2.10 ± 0.98 | |||||||||||||||||||
No | 145 | 2.2 ± 1.25 | ||||||||||||||||||||
Endometrioma | Yes | 98 | 2.08 ± 1.01 | |||||||||||||||||||
No | 145 | 2.16 ± 1.25 | ||||||||||||||||||||
Seckin | 2018 | Turkey | Retrospective | Caucasian | 267 | 2.30 ± 1.30 | 235 | 2.10 ± 1.20 | _ | _ | _ | _ | _ | _ | _ | _ | _ | _ | _ | _ | _ | 8 |
Kalem | 2019 | Turkey | Retrospective | Caucasian | 128 | 2.21 ± 0.80 | _ | _ | 85 | 1.66 ± 0.47 | _ | _ | _ | _ | _ | _ | _ | _ | 1.73 | 67 | 66 | 8 |
Targut | 2019 | Turkey | Retrospective | Caucasian | 121 | 2.18 ± 0.63 | 136 | 1.70 ± 0.59 | _ | _ | _ | _ | _ | _ | 17 | 1.90 ± 0.81 | 104 | 2.20 ± 0.62 | 1.60 | 88 | 45 | 7 |
Tas | 2019 | Turkey | Retrospective | Caucasian | 37 | 2.47 ± 1.01 | 40 | 2.05 ± 0.64 | 36 | 5.20 ± 3.68 | _ | _ | _ | _ | _ | _ | _ | _ | _ | _ | _ | 6 |
Biyik | 2020 | Turkey | Retrospective | Caucasian | 45 | 1.93 ± 0.78 | 42 | 1.84 ± 0.65 | _ | _ | _ | _ | _ | _ | _ | _ | _ | _ | _ | _ | _ | 6 |
Karadadas | 2020 | Turkey | Retrospective | Caucasian | 71 | 2.38 ± 0.14 | 77 | 2.37 ± 0.14 | _ | _ | _ | _ | _ | _ | _ | _ | _ | _ | _ | _ | _ | 7 |
Moini | 2020 | Iran | Retrospective | Caucasian | 217 | 5.50 ± 3.70 | 104 | 3.30 ± 2.90 | _ | _ | Deep lesions | Yes | 33 | 4.30 ± 2.90 | _ | _ | _ | _ | _ | _ | _ | 7 |
No | 104 | 3.30 ± 2.90 | ||||||||||||||||||||
Endometrioma | Yes | 184 | 5.70 ± 4.00 | |||||||||||||||||||
No | 104 | 3.30 ± 2.90 | ||||||||||||||||||||
Ottolani | 2020 | Italy | Prospective | Caucasian | 324 | 2.21 ± 0.95 | 284 | 2.05 ± 1.50 | _ | _ | Deep lesions | Yes | 69 | 2.12 ± 0.95 | 85 | 2.06 ± 0.81 | 239 | 2.25 ± 0.99 | _ | _ | _ | 7 |
No | 255 | 2.23 ± 0.93 | ||||||||||||||||||||
Peritoneal lesions | Yes | 41 | 2.04 ± 0.78 | |||||||||||||||||||
No | 283 | 2.2 ± 0.96 | ||||||||||||||||||||
Endometrioma | Yes | 41 | 2.04 ± 0.78 | |||||||||||||||||||
No | 110 | 2.090.88 | ||||||||||||||||||||
Chen,T | 2021 | China | Retrospective | East Asian | 137 | 1.69 ± 0.69 | 137 | 1.59 ± 0.47 | _ | _ | _ | _ | _ | _ | _ | _ | _ | _ | _ | _ | _ | 7 |
Chen,Z | 2021 | China | Retrospective | East Asian | 31 | 2.22 ± 0.93 | 95 | 2.31 ± 1.21 | _ | _ | _ | _ | _ | _ | _ | _ | _ | _ | _ | _ | _ | 6 |
Kedzia | 2021 | Poland | Prospective | Caucasian | 23 | 4.79 ± 3.11 | 10 | 1.66 ± 1.41 | _ | _ | _ | _ | _ | _ | _ | _ | _ | _ | _ | _ | _ | 6 |