Complete cytoreduction | Univariate | P value | Multivariate | P value | ||||
---|---|---|---|---|---|---|---|---|
(N%) | HR | 95% CI | HR | 95% CI | ||||
Age at recurrence (years) | ||||||||
< 60 | 17 (56.7) | 1 | ||||||
≥ 60 | 3 (42.9) | 1.744 | 0.331–9.189 | 0.512 | ||||
ECOG performance status before SCS | ||||||||
0 | 17 (53.1) | 1 | ||||||
1–2 | 3 (60.0) | 0.756 | 0.111–5.149 | 0.775 | ||||
FIGO stage at initial diagnosis | ||||||||
I/II | 16 (50.0) | 1 | ||||||
III/IV | 4 (80.0) | 0.250 | 0.025–2.489 | 0.237 | ||||
Histology | ||||||||
Uterine leiomyosarcoma | 9 (47.4) | 1 | ||||||
Low-grade endometrial stromal sarcoma | 6 (57.5) | 0.750 | 0.169–3.327 | 0.705 | ||||
High-grade endometrial stromal sarcoma | 2 (66.7) | 0.450 | 0.035–5.843 | 0.542 | ||||
Other | 3 (75.0) | 0.300 | 0.026–3.427 | 0.333 | ||||
Clinical symptoms at recurrence | ||||||||
No | 10 (52.6) | 1 | ||||||
Symptomatic | 10 (55.6) | 0.889 | 0.244–3.243 | 0.858 | ||||
Size of largest tumor (cm) | ||||||||
≤ 6 | 11 (57.9) | 1 | ||||||
> 6 | 9 (50.0) | 1.375 | 0.376–5.032 | 0.630 | ||||
Number of recurrent tumors | ||||||||
One | 12 (92.3) | 1 | 1 | |||||
Several | 8 (33.3) | 24.000 | 2.634-218.666 | 0.005 | 19.589 | 1.902-201.718 | 0.012 | |
DFI before SCS (months) | ||||||||
< 12 | 9 (40.9) | 1 | ||||||
≥ 12 | 11 (73.3) | 0.252 | 0.061–1.047 | 0.058 | ||||
Retroperitoneal lymph node metastasis | ||||||||
No | 19 (54.3) | 1 | ||||||
Yes | 1 (50.0) | 1.187 | 0.069–20.539 | 0.906 | ||||
Distant metastasis | ||||||||
No | 18 (54.5) | 1 | ||||||
Yes | 2 (50.0) | 1.200 | 0.150–9.570 | 0.863 | ||||
Peritoneal dissemination | ||||||||
No | 15 (68.2) | 1 | 1 | |||||
Yes | 5 (33.3) | 4.286 | 1.058–17.363 | 0.041 | 1.533 | 0.291–8.061 | 0.614 | |
Extended beyond the pelvis | ||||||||
No | 9 (47.4) | 1 | ||||||
Yes | 11 (61.1) | 0.573 | 0.155–2.117 | 0.403 | ||||
Ascites | ||||||||
None | 18 (52.9) | 1 | ||||||
Yes | 2 (66.7) | 0.563 | 0.046–6.806 | 0.651 |