Table 2 Effect of refusal of radiotherapy on overall survival of GC patients in different populations

AJCC I/II stage (n = 182,462)

Radiotherapy

Ref

Refuse of radiotherapy

1.64 (1.5–1.79)

< 0.001

AJCC III/IV stage (n = 25,631)

Radiotherapy

Ref

Refuse of radiotherapy

1.03 (0.84–1.25)

0.806

Years at diagnosis < 2000 (n = 35,014)

Radiotherapy

Ref

Refuse of radiotherapy

1.48 (1.22–1.79)

< 0.001

Years at diagnosis 2000–2013 (n = 140,339)

Radiotherapy

Ref

Refuse of radiotherapy

1.69 (1.54–1.85)

< 0.001

Years at diagnosis > 2013 (n = 32,740)

Radiotherapy

Ref

Refuse of radiotherapy

1.56 (1.19–2.03)

< 0.001

No surgery (n = 22,046)

Radiotherapy

Ref

Refuse of radiotherapy

1.29 (1.11–1.49)

< 0.001

Surgery (n = 186,047)

Radiotherapy

Ref

Refuse of radiotherapy

1.57 (1.42–1.72)

< 0.001