Skip to main content

Table 3 Univariate and multivariate logistic regression analyses of factors associated with refusal of radiotherapy in patients with stage I/II

From: Characteristics and survival of patients with gynecological cancers who refuse radiotherapy: a retrospective cohort study

Variables

Univariate analysis

Multivariate analysis

OR (95%CI)

P

OR (95%CI)

P

Age (years)

    

 <40

Ref

 

Ref

 

 40–65

1.43 (1.09–1.91)

0.013

1.60 (1.20–2.16)

0.002

 >65

3.32 (2.54–4.43)

< 0.001

2.89 (2.15–3.96)

< 0.001

Marital status at diagnosis

    

 Married

Ref

 

Ref

 

 Divorced

1.62 (1.33–1.97)

< 0.001

1.45 (1.19–1.76)

< 0.001

 Separated

1.51 (0.91–2.48)

0.109

1.46 (0.88–2.42)

0.142

 Single

1.32 (1.12–1.57)

0.001

1.34 (1.13–1.59)

< 0.001

 Widowed

2.34 (2.01–2.72)

< 0.001

1.35 (1.14–1.59)

< 0.001

Income ($)

    

 <36,580

Ref

 

Ref

 

 36,580–42,810

1.25 (1.09–1.42)

0.001

0.93 (0.79–1.11)

0.444

 >42,810

0.45 (0.37–0.53)

< 0.001

0.26 (0.20–0.33)

< 0.001

Unemployed

    

 <52.4%

Ref

 

Ref

 

 52.4-71.4%

1.53 (1.30–1.80)

< 0.001

0.88 (0.74–1.05)

0.164

 >71.4%

1.69 (1.45–1.99)

< 0.001

0.86 (0.67–1.10)

0.219

Education (less than high school)

    

 <18.75%

Ref

 

Ref

 

 18.75-28.20%

1.24 (1.06–1.44)

0.006

1.13 (0.96–1.33)

0.146

 >28.20%

1.30 (1.12–1.51)

0.001

0.81 (0.64–1.03)

0.080

Foreign born

    

 <5.04%

Ref

 

Ref

 

 5.04-15.66%

1.19 (1.03–1.39)

0.022

1.82 (1.51–2.19)

< 0.001

 >15.66%

1.10 (0.95–1.28)

0.214

1.60 (1.30–1.97)

< 0.001

Surgery

    

 Not Performed

Ref

 

Ref

 

 Recommended but not performed

5.91 (4.35–8.11)

< 0.001

5.52 (4.03–7.60)

< 0.001

 Yes

0.95 (0.74–1.23)

0.66

1.11 (0.86–1.46)

0.439

Grade

    

 Moderately differentiated (grade II)

Ref

 

Ref

 

 Poorly differentiated (grade III)

1.23 (1.06–1.43)

0.006

1.73 (1.49–2.01)

< 0.001

 Undifferentiated/anaplastic (grade IV)

1.28 (1.03–1.57)

0.021

2.39 (1.91–2.95)

< 0.001

 Well differentiated (grade I)

0.60 (0.50–0.71)

< 0.001

0.54 (0.45–0.64)

< 0.001

Primary site, n (%)

    

 Cervical cancer

Ref

 

Ref

 

 Endometrial cancer

1.12 (0.95–1.32)

0.181

1.05 (0.87–1.28)

0.597

 Ovarian cancer

0.11 (0.07–0.16)

< 0.001

0.13 (0.09–0.20)

< 0.001

 Vulvar cancer

1.46 (1.07–1.97)

0.014

1.18 (0.85–1.61)

0.323

Chemotherapy, n (%)

    

 Yes

Ref

 

Ref

 

 No/Unknown

0.24 (0.19–0.29)

< 0.001

0.28 (0.22–0.35)

< 0.001

  1. Note: OR, odds ratio; 95%CI, confidence interval
  2. Multivariate logistic regression analysis adjusted for age, marital status, income, unemployed, grade, education, foreign born, surgery, primary site, and chemotherapy