Table 2 Two-sample MR estimates of relationship between educational attainment and stress urinary incontinence
Exposure | MR Method | Stress urinary incontinence | Heterogeneity | Horizontal pleiotropy | ||||
|---|---|---|---|---|---|---|---|---|
No. of SNPs | OR (95% CI) | P-Value | Cochran’s Q | P-Value | Egger intercept | P-Value | ||
Years of schooling | IVW | 293 | 0.994 (0.992–0.996) | 7.764E-10 | 301.259 | 0.342 | -3.199E-05 | 0.565 |
MR-Egger | 0.996 (0.988–1.004) | 0.363 | ||||||
WM | 0.994 (0.992–0.997) | 7.666E-05 | ||||||
Simple mode | 0.994 (0.986–1.003) | 0.186 | ||||||
Weighted mode | 0.996 (0.988–1.003) | 0.261 | ||||||
Qualifications: College or University degree | IVW | 171 | 0.987 (0.983–0.991) | 1.217E-09 | 195.851 | 0.085 | 4.007E-05 | 0.659 |
MR-Egger | 0.982 (0.962–1.003) | 0.102 | ||||||
WM | 0.988 (0.982–0.994) | 2.988E-05 | ||||||
Simple mode | 0.984 (0.967–1.002) | 0.087 | ||||||
Weighted mode | 0.986 (0.971–1.001) | 0.072 | ||||||