Table 4 Health state utility values according to symptoms with no/little, moderate and large impact on daily life (respondents with uterus)

Symptoms with no or little impact on daily life

Sleep problems

0.949 (0.065)

0.897 (0.114)

0.931 (0.073)

−0.052

(−0.081, −0.023)

−0.034

(−0.072, 0.003)

Irritability

0.913 (0.109)

0.877 (0.104)

0.898 (0.072)

−0.037

(−0.075, 0.002)

−0.021

(−0.072, 0.030)

Exhaustion

0.934 (0.067)

0.904 (0.069)

0.879 (0.100)

−0.030

(−0.060, −0.001)

0.025

(−0.013, 0.063)

Anxiety

0.918 (0.084)

0.849 (0.113)

0.886 (0.075)

−0.069

(−0.110, −0.027)

−0.037

(−0.088, 0.014)

Hot flushes

0.916 (0.078)

0.885 (0.090)

0.870 (0.119)

−0.031

(−0.063, 0.001)

0.014

(−0.023, 0.051)

Joint discomfort

0.909 (0.107)

0.888 (0.109)

0.872 (0.162)

−0.021

(−0.078, 0.037)

0.016

(−0.056, 0.087)

Depression

0.897 (0.123)

0.901 (0.092)

0.887 (0.082)

0.004

(−0.045, 0.054)

0.014

(−0.053, 0.081)

Heart discomfort

0.897 (0.099)

0.846 (0.151)

0.858 (0.142)

−0.051

(−0.133, 0.031)

−0.012

(−0.104, 0.080)

LOI sexual activity

0.911 (0.065)

0.881 (0.115)

0.880 (0.110)

−0.030

(−0.068, 0.009)

0.001

(−0.041, 0.043)

Bladder problems**

0.912 (0.033)

0.773 (0.138)

0.889 (0.104)

−0.139

(−0.340, 0.062)

−0.115

(−0.294, 0.063)

Vaginal dryness

0.904 (0.060)

0.871 (0.103)

0.883 (0.152)

−0.033

(−0.085, 0.018)

−0.012

(−0.072, 0.047)

Symptoms with moderate impact on daily life

Sleep problems

0.905 (0.074)

0.863 (0.108)

0.860 (0.126)

−0.043

(−0.068, −0.018)

0.003

(−0.027, 0.033)

Irritability

0.896 (0.082)

0.838 (0.126)

0.830 (0.163)

−0.059

(−0.095, −0.022)

0.007

(−0.039, 0.054)

Exhaustion

0.900 (0.080)

0.842 (0.117)

0.855 (0.121)

−0.058

(−0.093, −0.023)

−0.013

(−0.052, 0.026)

Anxiety

0.880 (0.085)

0.844 (0.120)

0.853 (0.132)

−0.036

(−0.072, 0.001)

−0.009

(−0.053, 0.036)

Hot flushes

0.907 (0.092)

0.825 (0.151)

0.842 (0.124)

−0.083

(−0.136, −0.030)

−0.017

(−0.085, 0.051)

Joint discomfort

0.863 (0.102)

0.813 (0.149)

0.841 (0.124)

−0.050

(−0.102, 0.002)

−0.028

(−0.086, 0.030)

Depression

0.880 (0.094)

0.833 (0.132)

0.826 (0.147)

−0.047

(−0.099, 0.004)

0.007

(−0.049, 0.063)

Heart discomfort

0.882 (0.060)

0.745 (0.219)

0.818 (0.063)

−0.136

(−0.265, −0.008)

−0.073

(−0.248, 0.102)

LOI sexual activity

0.897 (0.073)

0.827 (0.136)

0.818 (0.159)

−0.071

(−0.131, −0.011)

0.008

(−0.060, 0.077)

Bladder problems

0.861 (0.123)

0.818 (0.114)

0.755 (0.133)

−0.043

(−0.184, 0.098)

0.064

(−0.098, 0.226)

Vaginal dryness

0.890 (0.103)

0.850 (0.130)

0.868 (0.102)

−0.040

(−0.109, 0.028)

−0.019

(−0.094, 0.057)

Symptoms with large impact on daily life

Sleep problems

0.889 (0.093)

0.813 (0.151)

0.859 (0.131)

−0.076

(−0.121, −0.030)

−0.046

(−0.096, 0.004)

Irritability

0.882 (0.084)

0.792 (0.157)

0.848 (0.136)

−0.091

(−0.152, −0.029)

−0.056

(−0.123, 0.011)

Exhaustion

0.869 (0.094)

0.818 (0.132)

0.804 (0.194)

−0.051

(−0.118, 0.016)

0.014

(−0.066, 0.094)

Anxiety

0.881 (0.084)

0.796 (0.163)

0.835 (0.136)

−0.085

(−0.155, −0.015)

−0.039

(−0.127, 0.050)

Hot flushes

0.865 (0.129)

0.792 (0.225)

0.716 (0.208)

−0.073

(−0.245, 0.099)

0.076

(−0.090, 0.242)

Joint discomfort

0.861 (0.086)

0.778 (0.155)

0.761 (0.162)

−0.083

(−0.179, 0.013)

0.017

(−0.072, 0.106)

Depression

0.891 (0.051)

0.737 (0.188)

0.820 (0.145)

−0.154

(−0.230, −0.078)

−0.084

(−0.180, 0.013)

Heart discomfort**

0.811 (0.074)

0.674 (0.180)

0.622 (0.201)

−0.137

(−0.380, 0.106)

0.052

(−0.103, 0.206)

LOI sexual activity

0.899 (0.090)

0.844 (0.100)

0.919 (0.066)

−0.055

(−0.114, 0.005)

−0.075

(−0.145, −0.004)

Bladder problems**

0.946 (0.076)

0.733 (0.127)

0.679 (0.274)

−0.213

(−0.650, 0.224)

0.054

(−0.328, 0.435)

Vaginal dryness

0.906 (0.081)

0.828 (0.117)

0.830 (0.165)

−0.078

(−0.169, 0.014)

−0.002

(−0.100, 0.096)