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Table 3 Pregnancy outcomes of the First and second FET cycle

From: Single versus double blastocyst transfer in first and second frozen-thawed embryo transfer cycle in advance-aged women: a two-center retrospective cohort study

Cycle rank

      

Cycle 1

 

SBT (n = 426)

DBT (n = 514)

Crude OR (95% CI)

P-value

Adjusted OR (95% CI) *

P-value

 

Live birth rate

170/426 (39.9)

269/514 (52.3)

1.65 (1.28–2.14)

< 0.001

1.65 (1.26–2.15) a

< 0.001

 

Clinical pregnancy rate

214/426 (50.2)

330/514 (64.2)

1.78 (1.37–2.31)0

< 0.001

1.78 (1.36–2.32)

< 0.001

 

Miscarriage rate

45/214 (21.0)

66/330 (20.0)

0.94 (0.61–1.44)

0.771

  

Cycle 2

 

SBT (n = 159)

DBT (n = 185)

Crude OR (95% CI)

P-value

Adjusted OR (95% CI) *

P-value

 

Live birth rate

53/159 (33.3)

82/185 (44.3)

1.52 (1.03–2.26)

0.037

1.30 (0.81–2.08) b

0.271

 

Clinical pregnancy rate

65/159 (40.9)

107/185 (57.8)

1.98 (1.29–3.05)

0.002

1.63 (1.03–2.60)

0.039

 

Miscarriage rate

12/65 (18.5)

26/107 (24.3)

1.42 (0.66–3.05)

0.371

  
  1. SBT Single blastocyst transfer, DBT Double blastocyst transfer, OR Odds ratio, CI Confidence interval
  2. *Adjusted for age, basal FSH, and N of good-quality blastocyst transferred (1 or 2 vs. 0)
  3. aP value = 0.883 for Hosmer-Lemeshow goodness-of-fit test, which did not indicate significant poor fit
  4. bP value = 0.370 for Hosmer-Lemeshow goodness-of-fit test, which did not indicate significant poor fit