Table 3 Data indicate changes in various factors in the vaginal microenvironment between different HPV infection groups
Variables | HPV-negative 898 cases | Transient HPV infection (n = 288) | Persistent HPV infection (n = 95) | P |
|---|---|---|---|---|
pH | ||||
Normal | 172 (19.15) | 27 (9.38) | 5 (5.26) | 0.037 |
Abnormal | 726 (80.85) | 252 (90.62) | 90 (94.74) | |
Microbiome density | ||||
Normal | 536 (59.69) | 167 (57.98) | 59 (62.11) | 0.117 |
Abnormal | 362 (40.31) | 121 (42.02) | 36 (37.89) | |
Microbiome diversity | ||||
Normal | 592 (65.92) | 156 (54.17) | 58 (61.05) | 0.095 |
Abnormal | 306 (34.08) | 132 (45.83) | 37 (38.95) | |
BV | ||||
Positive | 267 (29.73) | 135 (46.88) | 65 (68.42) | < 0.001 |
Negative | 631 (70.27) | 153 (53.12) | 30 (31.58) | |
AV | ||||
Positive | 215 (23.94) | 116 (41.13) | 69 (72.63) | < 0.001 |
Negative | 683 (76.06) | 172 (58.87) | 26 (27.37) | |
VVC | ||||
Positive | 152 (16.93) | 109 (37.85) | 57 (60.0) | < 0.001 |
Negative | 746 (83.07) | 179 (62.15) | 38 (40.0) | |
TV | ||||
Positive | 119 (13.26) | 89 (30.91) | 56 (58.95) | < 0.001 |
Negative | 779 (86.74) | 199 (69.09) | 39 (41.05) | |
CV | ||||
Positive | 177 (19.71) | 84 (29.17) | 61 (64.21) | < 0.001 |
Negative | 721 (80.29) | 204 (70.83) | 34 (35.79) | |
Leukocyte esterase | ||||
Positive | 699 (77.84) | 225 (78.13) | 81 (85.26) | 0.039 |
Negative | 199 (22.16) | 63 (21.87) | 14 (14.74) | |
Sialidase | ||||
Positive | 6 (0.67) | 3 (1.04) | 3 (3.16) | 0.047 |
Negative | 892 (99.33) | 285 (98.96) | 92 (96.84) | |
Catalase | ||||
Positive | 362 (40.31) | 158 (54.86) | 63 (66.31) | 0.029 |
Negative | 563 (59.69) | 130 (45.14) | 32 (33.69) | |
Lactobacillus | ||||
Positive | 405 (45.11) | 128 (44.44) | 52 (54.74) | 0.034 |
Negative | 493 (54.89) | 160 (55.56) | 43 (45.26) | |